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Dimefline hydrochloride

Dimefline hydrochloride structure

CAS No:
2740-04-7
Formula:
C20H21NO3.ClH
Chemical Name:
Dimefline hydrochloride
Synonyms:
4H-1-Benzopyran-4-one,8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-,hydrochloride (1:1);Flavone,8-[(dimethylamino)methyl]-7-methoxy-3-methyl-,hydrochloride;4H-1-Benzopyran-4-one,8-[(dimethylamino)methyl]-7-methoxy-3-methyl-2-phenyl-,hydrochloride;DW 62;Rec 7/0267;Dimefline hydrochloride;8-[(Dimethylamino)methyl]-7-methoxy-3-methylflavone hydrochloride;3-Methyl-7-methoxy-8-(dimethylaminomethyl)flavone hydrochloride;Remeflin;NSC 114650

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Description

Dimefline hydrochloride is an organic molecular entity.

Dimefline hydrochloride Basic Attributes

Molecular Weight：

359.84700

Exact Mass：

359.12900

EC Number：

220-366-7

UNII：

H0XB4R74ID

NSC Number：

114650

DSSTox ID：

DTXSID1046841

Characteristics

PSA：

42.68000

XLogP3：

4.64060

Melting Point：

213-214 °C

Boiling Point：

465.3ºC at 760 mmHg

Flash Point：

235.2ºC

Safety Information

hazard class code：

20/21/22

Precautionary statement(s)：

P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, P501

Hazard Statements：

H300

GHS Classification：

|Danger|H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]|P262, P264, P270, P280, P301+P310, P302+P350, P310, P321, P322, P330, P361, P363, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

dimefline

Computed Properties

Molecular Weight:359.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:359.1288213
Monoisotopic Mass:359.1288213
Topological Polar Surface Area:38.8
Heavy Atom Count:25
Complexity:493
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Drug Function and Efficacy

This product is a central nervous system stimulant that has a strong stimulating effect on the respiratory center of the medulla oblongata. Its effect is 100 times stronger than nikethamide, and the clinical recovery rate is as high as 90-95%. After intravenous injection, it can rapidly increase ventilation volume and reduce carbon dioxide partial pressure, and has a respiratory stimulating effect on all ventilation disorders, hypoventilation and hypercapnia.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

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Registered Holders

Jiangxi Boya Seehot Pharmaceutical Co., Ltd.

China
Active
Shanghai Ziyuan Pharmaceutical Co., Ltd.

China
Active
Pen Tsao Chemical & Pharmaceutical Industry Co., Ltd.

China
Active

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Guide of Dimefline hydrochloride

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Learn More Other Chemicals

Dimefline hydrochloride

SDS

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