Hexaethylene glycol
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Hexaethylene glycol
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CAS No:
2615-15-8
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Formula:
C12H26O7
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Chemical Name:
Hexaethylene glycol
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Synonyms:
3,6,9,12,15-Pentaoxaheptadecane-1,17-diol;Hexaethylene glycol;Hexaoxyethylene glycol;Ethanol,2,2′-[oxybis(oxy-2,1-ethanediyloxy-2,1-ethanediyloxy)]bis-;Hexagol;NSC 201209;2-[2-[2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
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CAS No:
Description
Hexaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hexaethylene glycol is a poly(ethylene glycol).
Characteristics
86.6
-1.9
viscous colourless liquid
1.0948 g/cm3 @ Temp: 60 °C
5-7 °C
217 °C
193.7±26.5 °C
1.460
0.000317mmHg at 25°C
Safety Information
NONH for all modes of transport
2
S23-S24/25
MM3670000
Stable. Incompatible with strong oxidizing agents.
P264, P280, P305+P351+P338, P33, P313
H319
|Warning|H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 73 companies from 3 notifications to the ECHA C&L Inventory.
Hexaethylene glycol Use and Manufacturing
Substrate employed in the synthesis of binaphthol-based macrocyclic ethers using intramolecular oxidative coupling with CuCl(OH)-TMEDA.1 Hexaethylene Glycol is part of a leaf extract (Murdannia Bracteata) which exhibits antioxidant, antimicrobial and anti-cancer properties. It also shows potential application as functional hydraulic fl uids.
EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives|Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern|Cosmetics -> Humectant; Solvent
Computed Properties
Molecular Weight:282.33
XLogP3:-1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:16
Exact Mass:282.16785316
Monoisotopic Mass:282.16785316
Topological Polar Surface Area:86.6
Heavy Atom Count:19
Complexity:141
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Hydrophilic agent and solubilizer, improves the solubility and stability of formulations; may enhance skin hydration and act as a penetration enhancer.
Recommended Suppliers of Hexaethylene glycol
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CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives -
CN
1 YR
Business licensedTrader Supplier of pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals,Octadecanedioic acid,Eicosanedioic AcidInquiryCAS No.: 2615-15-8Grade: Pharmaceutical GradeContent: 99% -
CN
1 YR
Business licensedTrader Supplier of PEG
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