2,7-Dichlorobenzothiazole
-
2,7-Dichlorobenzothiazole
structure -
-
CAS No:
2942-23-6
-
Formula:
C7H3Cl2NS
-
Chemical Name:
2,7-Dichlorobenzothiazole
-
Synonyms:
2,7-Dichlorobenzo[d]thiazole;2,7-dichlorobenzothiazole;2,7-dichloro-1,3-benzothiazole;2,7-Dichloro benzothiazole;BENZOTHIAZOLE, 2,7-DICHLORO-;Benzothiazole,2,7-dichloro-;SCHEMBL1851438;CTK4G3282;KS-00000QIO;DTXSID70462272
-
CAS No:
2,7-Dichlorobenzothiazole Use and Manufacturing
General procedure: A mixture of the 2-mercaptobenzo[d]thiazole (>1 g, 1 equiv) and sul-furyl chloride (10 equiv) was stirred at 20–25 °C for 15 min. Next, H 2 O(2 equiv) was added and the mixture was stirred at 20–25 °C for anadditional 3 h. A sample was taken, quenched with MeCN/H 2 O (2:1)and analyzed by HPLC. After completion of the reaction, the mixturewas diluted with MeCN (5 volumes) and slowly quenched with H 2 O(20 volumes). The product precipitated from the aqueous solution.The solid was collected and washed with H 2 O. Drying under vacuumafforded the pure product. In the case of the liquid product 2-chloro-benzo[d]thiazole (13), the reaction mixture was extracted withEtOAc. The organic layer was then dried and concentrated to affordthe product as an oil.