Retinoyl β-glucuronide
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Retinoyl β-glucuronide
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CAS No:
401-10-5
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Formula:
C26H36O8
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Chemical Name:
Retinoyl β-glucuronide
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Synonyms:
β-D-Glucopyranuronic acid,1-retinoate;Retinoic acid,1-ester with β-D-glucopyranosiduronic acid;Retinoic acid,1-ester with glucopyranuronic acid;Glucopyranosiduronic acid,1-retinoate,β-D-;Retinoic acid,β-D-glucopyranuronic acid deriv.;Retinoyl β-glucuronide;all-trans-Retinoyl glucuronide;all-trans-Retinoyl β-D-glucuronide;Retinoic acid,β-D-glucuronosyl ester;30259-72-4;1004517-36-5
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CAS No:
Description
Yellow Solid
Solid
1-O-all-trans-retinoyl-beta-glucuronic acid is a retinoid that is retinoic acid in which the carboxy proton has been replaced by a beta-D-glucuronyl residue. It has a role as a human metabolite. It is a member of glucuronic acids and a retinoid. It derives from an all-trans-retinoic acid. It is a conjugate acid of a 1-O-(all-trans-retinoyl)-beta-D-glucuronate.
Drug Information
All-trans-retinoyl glucuronide is a known human metabolite of Tretinoin.
13-cis-retinoyl glucuronide
Retinoyl β-glucuronide Use and Manufacturing
A biliary metabolite of Vitamin A, occurs endogenously in human blood.RAG is biologically active in promoting the growth of vitamin A-deficient rats and the the induction of differentiation of HL-60 and BA-HAN-1C cells, but less cytotoxic than Retinoic Acids.
Computed Properties
Molecular Weight:476.6
XLogP3:4.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:476.24101810
Monoisotopic Mass:476.24101810
Topological Polar Surface Area:134
Heavy Atom Count:34
Complexity:921
Defined Atom Stereocenter Count:5
Defined Bond Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Learn More Other Chemicals
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9-cis Retinoyl b-D-Glucuronide
153321-67-6
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13-cis Retinoyl b-D-Glucuronide
78147-42-9