Sodium glycolate
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Sodium glycolate
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CAS No:
2836-32-0
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Formula:
C2H4O3.Na
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Chemical Name:
Sodium glycolate
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Synonyms:
Acetic acid,2-hydroxy-,sodium salt (1:1);Glycolic acid,monosodium salt;Acetic acid,hydroxy-,monosodium salt;Sodium glycolate;Sodium α-hydroxyacetate;Sodium hydroxyacetate;Hydroxyacetic acid sodium salt;Glycolic acid sodium salt
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CAS No:
Description
White to off-white powder
Liquid
Sodium glycolate is an organic sodium salt comprising equal numbers of sodium and glycolate ions. It has a role as a keratolytic drug. It contains a glycolate.
Characteristics
60.4
White to off-white Powder
1.416g/cm3
151 °C
265.6°C at 760 mmHg
128.7ºC
H2O: soluble
Safety Information
36/37/38
24/25-26
MC5525000
Xi
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Danger|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 411 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Drug Information
Agents that soften, separate, and cause desquamation of the cornified epithelium or horny layer of skin. They are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. (See all compounds classified as Keratolytic Agents.)
glycolate
Sodium glycolate Use and Manufacturing
By the reaction of chloroacetic acid and sodium hydroxide. Dissolve monochloroacetic acid in distilled water, carefully add liquid alkali to adjust the pH to 9. With the addition of alkali, the temperature continues to rise, and finally to boiling, continue to keep at 80-100 ℃ for 2h, during which the pH value is not lower than 9. Then concentrate until thin film appears on the liquid surface, add appropriate amount of distilled water and filter while it is hot, and cool the filtrate to about 15°C, filter the crystals, and then refine the finished product.
Used in organic synthesis intermediates.
Fillers
Cleaning and furnishing care products
100,000 - 500,000 lb
All other chemical product and preparation manufacturing|Acetic acid, 2-hydroxy-, sodium salt (1:1): ACTIVE
Computed Properties
Molecular Weight:98.03
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:97.99798824
Monoisotopic Mass:97.99798824
Topological Polar Surface Area:60.4
Heavy Atom Count:6
Complexity:44.1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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