 Home > Encyclopedia > Calcium dobesilate

Calcium dobesilate

Calcium dobesilate structure

CAS No:
20123-80-2
Formula:
C6H6O5S.¹/2Ca
Chemical Name:
Calcium dobesilate
Synonyms:
Benzenesulfonic acid,2,5-dihydroxy-,calcium salt (2:1);Hydroquinone calcium sulfonate;Calcium bis(2,5-dihydroxybenzenesulfonate);Calcium dobesilate;Calcium p-dihydroxybenzenesulfonate;Doxium;Dobesilate calcium;2,5-Dihydroxybenzenesulfonic acid calcium salt;Calcium 2,5-dihydroxybenzenesulfonate;205E;Dobesilate calcium salt;Hydroquinone calcium sulfate;Dexium;29138-74-7;39038-15-8
Categories:
Active Pharmaceutical Ingredients > Circulatory System Drugs

Request for Quotation

Description

White or almost white, hygroscopic powder.

A drug used to reduce hemorrhage in diabetic retinopathy.

Calcium dobesilate Basic Attributes

Molecular Weight：

418.41

Exact Mass：

417.93413

EC Number：

243-531-5

UNII：

5921X1560Q

DSSTox ID：

DTXSID60173946

ATC Code：

C - Cardiovascular system

HScode：

2924299090

Characteristics

PSA：

212

XLogP3：

2.16540

Appearance：

white to beige

Melting Point：

>300 °C (decomp)

Water Solubility：

H2O: soluble15mg/mL, clear

Storage Conditions：

room temp

Toxicity：

LD50 in mice: 700 mg/kg (Esteve-Subirana)

Safety Information

Hazard category：

IRRITANT

wgk germany：

hazard class code：

36/37/38

safety instructions：

Marks：

Precautionary statement(s)：

P261; P305 + P351 + P338

Hazard Statements：

H315; H319; H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, and P362|Aggregated GHS information provided by 3 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure. (See all compounds classified as Hemostatics.)

MeSH Entry Terms：

2,5 Dihydroxybenzenesulfonate

Calcium dobesilate Use and Manufacturing

Vasotropic/ Venous Disorders

Computed Properties

Molecular Weight:418.4
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:10
Exact Mass:417.9341297
Monoisotopic Mass:417.9341297
Topological Polar Surface Area:212
Heavy Atom Count:25
Complexity:228
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes

Drug Function and Efficacy

It regulates the physiological function of the microvascular wall, reduces plasma viscosity, reduces platelet aggregation and other mechanisms, thereby regulating the microcirculation function and playing a role in treating retinal microcirculation lesions caused by diabetes.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Calcium Dobesilate Capsules
Ingredients	The main ingredient of this product is calcium dobesilate.
Indication	This product needs to be used in combination with hypoglycemic drugs. Consult a physician before using this product for the first time. Regular hospital check-ups are required during treatment. It is not recommended for women in the first 3 months of pregnancy and during breastfeeding. It is contraindicated for those who are allergic to this product, and should be used with caution by those with allergic constitutions. It is prohibited to use this product when its properties change. Keep this product out of reach of children. If you are using other medicines, please consult a physician or pharmacist before using this product.
Specifications	0.25g/tablet
Manufacturer	Kangya of Ningxia Pharmaceutical Co., Ltd.

Calcium Dobesilate

Calcium Dobesilate Capsules
Ingredients	The main ingredient of this product is calcium dobesilate.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	0.25g (based on C12H10CaO10S2)
Manufacturer	Shanghai Haihong Industry (Group) Chaohu Jinchen Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Kangya of Ningxia Pharmaceutical Co., Ltd.

China
Active
Hubei Guangchen Pharmaceutical Co., Ltd.

China
Active
Jiangxi Boya Seehot Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Calcium dobesilate

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

Calcium dobesilate 10KG

CAS No.: 20123-80-2

Grade: Pharmaceutical Grade

Content: 98%

Inquiry
Shandong zhishang chemical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of Dichloromethane,Linocaine hydrochloride

Hot Sale Pharmaceutical Intermediates Calcium Dobesilate CAS No. 20123-80-2

CAS No.: 20123-80-2

Inquiry
Shandong Airuike Chemical Co., Ltd. Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals,CATALYST AND AUXILIARY,FLAVORS AND FRAGRANCES,Chemical Pesticides,ADDITIVE

Pharmaceutical Intermediates Calcium Dobesilate CAS No. 20123-80-2

CAS No.: 20123-80-2

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Shandong Ailike New Material Technology Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of API,Antibiotics,Anti cancer category

High quality and low price Pharmaceutical Intermediates Calcium Dobesilate CAS No. 20123-80-2

CAS No.: 20123-80-2

Grade: pharmaceutical grade

Content: 99.9%

Inquiry