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Tenuifolin

Tenuifolin structure

Tenuifolin 

structure
  • CAS No:

    20183-47-5

  • Formula:

    C36H56O12

  • Chemical Name:

    Tenuifolin

  • Synonyms:

    Olean-12-ene-23,28-dioic acid,3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-,(2β,3β,4α)-;Olean-12-ene-23,28-dioic acid,3β-(β-D-glucopyranosyloxy)-2β,27-dihydroxy-;Glucopyranoside,2β,3β,27-trihydroxyolean-12-ene-23,28-dioic acid-3,β-D-;(2β,3β,4α)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic acid;Tenuifolin;Presenegenin-3-O-glucoside;Tenuifoline

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1].

Tenuifolin Basic Attributes

680.8

680.82

29389090

Characteristics

214.44000

2.25

1.4±0.1 g/cm3

201-204 °C @ Solvent: Methanol

853.6±65.0 °C at 760 mmHg

262.2±27.8 °C

1.623

Safety Information

24/25

Drug Information

tenuifolin

Computed Properties

Molecular Weight:680.8
XLogP3:2.2
Hydrogen Bond Donor Count:8
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:6
Exact Mass:680.37717722
Monoisotopic Mass:680.37717722
Topological Polar Surface Area:214
Heavy Atom Count:48
Complexity:1330
Undefined Atom Stereocenter Count:15
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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