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Home > Encyclopedia > DL-ADRENALINE HYDROCHLORIDE

DL-ADRENALINE HYDROCHLORIDE

DL-ADRENALINE HYDROCHLORIDE structure

DL-ADRENALINE HYDROCHLORIDE 

structure
  • CAS No:

    329-63-5

  • Formula:

    C9H14ClNO3

  • Chemical Name:

    DL-ADRENALINE HYDROCHLORIDE

  • Synonyms:

    (±)-4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol hydrochloride;Adrenaline Hcl, racepinephrine hcl;(±)-Epinephrine hydrochloride,(±)-Adrenalin, 4-(1-Hydroxy-2-[methylamino]ethyl)-1,2-benzenediol hydrochloride;Racepinephrine/Adrenaline HCL;Adrenalin HCL;1,2-Benzenediol, 4-1-hydroxy-2-(methylamino)ethyl-, hydrochloride;rs-epinephrine hcl;RACEPINEPHRINEHYDROCHLORIDE,USP

  • Categories:

    Organic Chemistry  >  Amides

Description

solid


A racemic mixture of d-epinephrine and l-epinephrine.


Epinephrine (adrenalin) is synthesized from norepinephrine (noradrenalin) by the action of the enzyme phenylethanolamineN-methyltransferase. Epinephrine comprises 5%-10% of the total catecholamines in the central nervous system. It is a mixed α/β-adrenergic receptor agonist and stimulates these receptors. Their site of synthesis is adrenal medulla and it travels through the vascular systems. Its breakdown occurs in the central nervous system (CNS), liver and kidney.

DL-ADRENALINE HYDROCHLORIDE Basic Attributes

219.67

219.066

206-346-0

TSCA listed

DTXSID9057717

2937901500

Characteristics

72.7

1.54350

solid

1.283 g/cm3

157°

413.1ºC at 760 mmHg

207.9ºC

H2O: 50mg/mL

2-8°C

Safety Information

II

6.1(a)

2811

3

T

26-36/37-45

DO3330000

T

Stable, but light sensitive. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.

P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P403+P233, P405, P501

24/25-36/37/38

UN 2811 6.1/PG 2

Drug Information

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)|Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics. (See all compounds classified as Mydriatics.)|Drugs that selectively bind to and activate alpha adrenergic receptors. (See all compounds classified as Adrenergic alpha-Agonists.)|Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)|Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)|Drugs that selectively bind to and activate beta-adrenergic receptors. (See all compounds classified as Adrenergic beta-Agonists.)

Adrenaline Hydrochloride, Racemic Mixture

DL-ADRENALINE HYDROCHLORIDE Use and Manufacturing

Uses

bronchodilatator, An adrenergic receptor agonist.


bronchodilatator,


(±)-Epinephrine hydrochloride has been used:in the induction of renalase expression in Human renal proximal tubular epithelial cellsin the infusion studies to test its effect on heart rate and eye temperature measurements in bullas a medium supplement for the stimulation of endothelial progenitor cells

1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride (1:1): ACTIVE

Computed Properties

Molecular Weight:219.66
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:219.0662210
Monoisotopic Mass:219.0662210
Topological Polar Surface Area:72.7
Heavy Atom Count:14
Complexity:154
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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