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Home > Encyclopedia > 2-(Chloromethyl)tetrahydrofuran

2-(Chloromethyl)tetrahydrofuran

2-(Chloromethyl)tetrahydrofuran structure

2-(Chloromethyl)tetrahydrofuran 

structure
  • CAS No:

    3003-84-7

  • Formula:

    C5H9ClO

  • Chemical Name:

    2-(Chloromethyl)tetrahydrofuran

  • Synonyms:

    Furan,2-(chloromethyl)tetrahydro-;2-(Chloromethyl)tetrahydrofuran;Tetrahydrofurfuryl chloride;2-(Chloromethyl)oxolane;NSC 2874;154533-73-0

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Colorless to light yellow liqui

2-(Chloromethyl)tetrahydrofuran Basic Attributes

120.577

120.58

221-102-3

2874

2932190090

Characteristics

9.23000

0.72

Colorless to light yellow liquid

1.110 g/cm3 @ Temp: 25 °C

150-151 °C

47.8±0.0 °C

1.440

2-8ºC

Safety Information

III

3

UN 1993 3/PG 3

3

R10;R36/37/38

S26-S36/37/39-S24/25-S16

LU0350000

Xi:Irritant;

Stable under normal temperatures and pressures.

P261-P305 + P351 + P338

H226-H315-H319-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

|Warning|H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]|P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501|Aggregated GHS information provided by 46 companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Provide a low-stimulus environment. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Treat frostbite by rapid rewarming ... . /Ethers and related compounds/|Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Treat seizures with diazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Ethers and related compounds/

2-(Chloromethyl)tetrahydrofuran Use and Manufacturing

98%

Furan, 2-(chloromethyl)tetrahydro-: ACTIVE

Computed Properties

Molecular Weight:120.58
XLogP3:1.2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:120.0341926
Monoisotopic Mass:120.0341926
Topological Polar Surface Area:9.2
Heavy Atom Count:7
Complexity:56
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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