2-Fluoroacetyl chloride

96.488

96.49

206-623-6

0CQX1ANG4H

2810|1752

DTXSID4059885

2915900090

17.07000

0.52

Fluoroacetyl chloride is a liquid. (EPA, 1998)

1.3813 g/cm³ @ Temp: 20 °C

70-71 °C @ Press: 755 Torr

-16.1±19.0 °C

1.353

Reacts with water or moisture in air to form hydrochloric acid (hydrogen chloride)

Halogenated Organic Compounds

Water-Reactive

FLUOROACETYL CHLORIDE, an acid halide, when heated to decomposition, emits very toxic fumes of chlorine and fluorine-containing compounds. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

6.1(a)

UN 2922

14-26-35

3/7-9-38-45-53

C: Corrosive;

P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, P501

H314

When heated to decomposition, it emits very toxic fumes of chlorine and fluorine-containing compounds. (Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Some of these materials may ignite combustibles (i.e., wood, paper, oil, etc.) or react violently with water. (EPA, 1998)

(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Spray cooling water on containers that are exposed to flames until well after fire is out. Move container from fire area if you can do so without risk. Do not get water in container, as material may react violently with water. (Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam. (EPA, 1998)

Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

(Non-Specific -- Chloroacetyl Chloride and Fluoroacetic Acid) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Do not touch spilled material; stop leak if you can do so without risk. Use water spray to reduce vapors (may react violently with water). Small spills: absorb with sand or other non-combustible absorbent material and place into containers for later disposal. Large spills: dike far ahead of spill for later disposal. (EPA, 1998)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Fluoroacetyl chloride is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 10 lbs.

Highly toxic by inhalation. (Non-Specific -- Chloroacetyl Chloride) Corrosive to skin and irritating to eyes. (EPA, 1998)

Warning: There is no known antidote for fluoroacetate intoxication. Symptomatic and supportive care should be provided. Highly toxic by inhalation; corrosive to the skin and irritating to the eyes. Delayed convulsant. Effects usually appear within 30 minutes of exposure but may be delayed as long as 20 hours. Caution is advised. Vital signs should be monitored closely. Signs and Symptoms of Fluoroacetyl Chloride Exposure: Signs and symptoms may be extremely severe and range from nausea, excessive salivation, vomiting, diarrhea, blurred vision, tingling sensations, and muscular twitching to convulsions alternating with coma and depression, and heart failure. Other symptoms include numbness, low blood pressure, hyperactivity, respiratory depression or arrest, cyanosis (blue tint to the skin and mucous membranes), and ventricular fibrillation. Emergency Life-Support Procedures: Acute exposure to fluoroacetyl chloride may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination. Inhalation Exposure: 1. Move victims to fresh air. Emergency personnel should avoid self-exposure to fluoroacetyl chloride. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures. 4. Rush to a health care facility. Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self-exposure to fluoroacetyl chloride. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support. 3. Remove contaminated clothing and shoes as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin, including hair and nails, vigorously and thoroughly with soap and water. 6. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures. 7. Rush to a health care facility. Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support. 2. Obtain authorization and/or further instructions form the local hospital for performance of other invasive procedures. 3. DO NOT induce vomiting. 4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water. 5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. 6. Rush to a health care facility. (EPA, 1998)

Acetyl chloride, 2-fluoro-: ACTIVE