Dioxanone

In a typical experiment, oxidation of 1, 4 dioxane with O2 was performed in a 25 mL two-necked round bottom flask equipped with a reflux condenser; filled with 10 mmol of 1, 4 dioxane, and 150 mg of catalyst. The reaction mixture was heated at 80 °C under gentle stirring. At atmospheric pressure, O2 gas from a balloon was bubbled into the reaction mixture at a certain stable flow rate controlled by a mass flow controller. Care should be taken while heating the reaction mixture as dioxane vapours can form a highly combustible mixture with pure oxygen and form explosive peroxides (MSDS 1, 4 dioxane). After 24 h, the catalyst was separated from the reaction mixture by simple filtration and the reaction mixture after proper dilution with methanol was analyzed using GC–MS.Example 1-1[22] A catalyst tower made of a cylindrical stainless tube measuring 9 cm in internal diameter and 160 cm in height, in which 8 kg of a catalyst had been loaded, was equipped at a 2OL reactor. Then, 15 kg of diethylene glycol was supplied to the reactor. Hydrogen was supplied to the catalyst tower through the reactor at a rate of 600 mL per minute. The reactor and the catalyst tower were heated to a temperature of 230-2350C and 245-2550C, respectively.[23] By controlling the heat source of the reactor, diethylene glycol was vaporized so that the diethylene glycol could be supplied at a rate of 450-470 mL per hour. After 30 hours of reaction, 1431 g of a crude EXAMPLE; About 36.8 grams of crude On top of a catalyst bed comprising a cylindrical stainless steel tube having an inner diameter of 6 cm and a height of 100 cm equipped with 5 kg of a copper-chromium (Cu-Cr) catalyst, DEG was introduced at a rate of 2.0 ml / min using a metering pump, and hydrogen was introduced at a flow rate of 2.5 L / min using a flow meter. The catalyst bed was heated via a block heater to a temperature of 280 C. The crude para-dioxanone discharged to the bottom was recovered, sampled daily, and the purity was measured by gas chromatography. The purity measurement results are shown in Fig. According to FIG. 2, the purity of crude para-dioxanone was 75% at the beginning of the reaction, but then decreased to 50% after 25 days. From this, it can be seen that the lifetime of the catalyst was drastically reduced as the reaction time elapsed.

Molecular Weight:102.09
XLogP3:-0.2
Hydrogen Bond Acceptor Count:3
Exact Mass:102.031694049
Monoisotopic Mass:102.031694049
Topological Polar Surface Area:35.5
Heavy Atom Count:7
Complexity:79
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes