C2-Ceramide
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C2-Ceramide
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CAS No:
3102-57-6
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Formula:
C20H39NO3
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Chemical Name:
C2-Ceramide
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Synonyms:
Acetamide,N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-;Acetamide,N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-,(E)-D-erythro-;Acetamide,N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-,[R-[R*,S*-(E)]]-;Acetamide,N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-;N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide;N-Acetyl-C18-sphingosine;D-erythro-1,3-Dihydroxy-2-acetamido-trans-4-octadecene;N-Acetylsphingosine;D-erythro-C2-Ceramide;C2-Ceramide;D-erythro-N-Acetylsphingosine;N-Acetyl-D-erythro-sphingosine;N-Acetyl-D-sphingosine;Ceramide 2;532-45-6
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CAS No:
Description
C2 Ceramide (Ceramide 2) is the main lipid of the stratum corneum and a protein phosphatase 1 (PP1) activator. C2 Ceramide activates PP2A and ceramide-activated protein phosphatase (CAPP). C2 Ceramide induces cells differentiation and apoptosis, inhibits mitochondrial respiratory chain complex III. C2 Ceramide is also a skin conditioning agent that protects the epidermal barrier from water loss[1][2][3][4][5].
C2-Ceramide Use and Manufacturing
A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2
