10-[(1-Methyl-3-piperidyl)methyl]phenothiazine
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![10-[(1-Methyl-3-piperidyl)methyl]phenothiazine structure](https://file.echemi.com/fileManage/upload/canonicalSmiles/20220812/2dc34466a1b941e1a0df471e407fb8d8.png "10-[(1-Methyl-3-piperidyl)methyl]phenothiazine")
10-[(1-Methyl-3-piperidyl)methyl]phenothiazine
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CAS No:
60-89-9
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Formula:
C19H22N2S
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Chemical Name:
10-[(1-Methyl-3-piperidyl)methyl]phenothiazine
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Synonyms:
10H-Phenothiazine,10-[(1-methyl-3-piperidinyl)methyl]-;Phenothiazine,10-[(1-methyl-3-piperidyl)methyl]-;10-[(1-Methyl-3-piperidinyl)methyl]-10H-phenothiazine;Lacumin;Mepazine;Mepazine base;(N-Methyl-3-piperidyl)methylphenothiazine;10-[(1-Methyl-3-piperidyl)methyl]phenothiazine;Pacatal;Pacatal base;Pakatal;Pecatal;Pecazine;Meprazine;Mepazin;III 2318;Paxital;MPMP;Nothiazine;P 391;Pacatol;Mesapin;10-[(1-Methylpiperidin-3-yl)methyl]phenothiazine
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CAS No:
Description
Mepazine (Pecazine) is a potent and selective MALT1 inhibitor. Mepazine inhibits GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 and 0.42 μM, respectively. Mepazine affects viability of ABC-DLBCL cells by enhancing apoptosis[1].
Pecazine is a member of phenothiazines.
10-[(1-Methyl-3-piperidyl)methyl]phenothiazine Basic Attributes
310.459
310.46
200-490-8
DTXSID2046177
2934300000
Computed Properties
Molecular Weight:310.5
XLogP3:5.6
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:310.15036988
Monoisotopic Mass:310.15036988
Topological Polar Surface Area:31.8
Heavy Atom Count:22
Complexity:352
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
10-[(1-Methyl-3-piperidyl)methyl]phenothiazine
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