 Home > Encyclopedia > Formamidine acetate

Formamidine acetate

Formamidine acetate structure

CAS No:
3473-63-0
Formula:
C2H4O2.CH4N2
Chemical Name:
Formamidine acetate
Synonyms:
Methanimidamide,acetate (1:1);Formamidine,monoacetate;Methanimidamide,monoacetate;Formamidine acetate;Formamidinium acetate;Methanimidamide acetate;Formamidine acetate (1:1);NSC 96608;Formimidamide acetate;Acetic acid methanimidamide;40730-94-7;87667-19-4;146797-05-9
Categories:
Chemical Reagents > Organic Reagents

Request for Quotation

Description

white to light yellow crystalline powder

Formamidine acetate Basic Attributes

Molecular Weight：

104.11

Exact Mass：

104.058578

BRN：

3563488

EC Number：

222-442-5

NSC Number：

96608

DSSTox ID：

DTXSID3063047

HScode：

29252000

Characteristics

PSA：

87.2

Appearance：

Clear colorless to light yellow Liquid

Density：

1.124

Melting Point：

162-164 °C

Flash Point：

40ºC

Water Solubility：

H2O: 832 g/L (21 ºC)

Storage Conditions：

-20°C

Toxicity：

LD50 orally in Rabbit: 2510 mg/kg LD50 dermal Rat > 2000 mg/kg

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

43-36/37/38

safety instructions：

36/37-37/39-26-36/37/39-27

Marks：

Precautionary statement(s)：

P280

Hazard Statements：

H317

GHS Classification：

|Warning|H315 (13.59%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 103 companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

formamidine

Formamidine acetate Use and Manufacturing

Methods of Manufacturing

It is derived from triethyl orthoformate and glacial acetic acid through ammonia condensation. Add triethyl orthoformate to glacial acetic acid and heat, pass ammonia to react for 1.5h, and precipitate white crystals, then continue to pass ammonia for half an hour. The reactant is firstly distilled at atmospheric pressure, and then the alcohol is evaporated by vacuum distillation. Cool to 25°C, wash with absolute ethanol, filter, and dry to obtain formamidine acetate.

Uses

Methylacetate acetate is mainly used for the synthesis of a class of compounds with biological activity such as the anti-tumor drug 4-hydroxy-5-fluoropyrimidine, etc., as well as the synthesis of cyclohexanone peptide antifungal drugs, the synthesis of trichloropyrimidine, etc.

Manufacturing Info：

Methanimidamide, acetate (1:1): ACTIVE

Computed Properties

Molecular Weight:104.11
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Exact Mass:104.058577502
Monoisotopic Mass:104.058577502
Topological Polar Surface Area:87.2
Heavy Atom Count:7
Complexity:41.3
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Recommended Suppliers of Formamidine acetate

Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
4 YRS

Business licensed Certified factory

Manufactory Supplier of Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst,Chemical Materials,Chem&Pharm Intermediates,Organic Intermediates,Feed Additive

Formamidine acetate & C3H8N2O2 99% Solid Dideu

CAS No.: 3473-63-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Formamidine acetate

CAS No.: 3473-63-0

Content: 99.00%

Inquiry
HANGZHOU HAILAN CHEMICAL CO.,LTD Contact Supplier

CN
4 YRS

Business licensed

Trader Supplier of intermediates ,fine chemical,food additives

Formamidine acetate HL

CAS No.: 3473-63-0

Inquiry
Shandong Ailike New Material Technology Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of API,Antibiotics,Anti cancer category

Formamidine Acetate CAS 3473-63-0

CAS No.: 3473-63-0

Grade: pharmaceutical grade

Content: 99.9%

Inquiry
Shanghai Lonwin Chemical Co.,Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of CHEMICALS,REAGENTS

High quality Formamidine acetate CAS NO.3473-63-0

CAS No.: 3473-63-0

Grade: Pharmaceutical Grade

Content: 99%

Inquiry