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Home > Encyclopedia > (2,4-Dinitrophenyl)hydrazine

(2,4-Dinitrophenyl)hydrazine

(2,4-Dinitrophenyl)hydrazine structure

(2,4-Dinitrophenyl)hydrazine 

structure
  • CAS No:

    119-26-6

  • Formula:

    C6H6N4O4

  • Chemical Name:

    (2,4-Dinitrophenyl)hydrazine

  • Synonyms:

    Hydrazine,(2,4-dinitrophenyl)-;(2,4-Dinitrophenyl)hydrazine;1-Hydrazino-2,4-dinitrobenzene;DNPH;NSC 5709;1-(2,4-Dinitrophenyl)hydrazine;2,4-Dinitrobenzenehydrazine

  • Categories:

    Chemical Reagents  >  Organic Reagents

Description

white to light yellow crystal powdeChEBI: A C-nitro compound that is phenylhydrazine substituted at the 2- and 4-positions by nitro groups.2,4-Dinitrophenylhydrazine (abbreviated 2,4-DNP for short) is the chemical compound C6H3 (NO2) 2NHNH2, and it is often used to qualitatively test for carbonyl groups associated with aldehydes and ketones. The hydrazone derivatives can also be used as evidence toward the identity of the original compound. It is relatively sensitive to shock and friction; it


2,4-dinitrophenylhydrazine is a C-nitro compound that is phenylhydrazine substituted at the 2- and 4-positions by nitro groups. It has a role as a reagent. It is a member of phenylhydrazines and a C-nitro compound.

(2,4-Dinitrophenyl)hydrazine Basic Attributes

198.14

198.14

615586

204-309-3

1N39KD7QPJ

5709

DTXSID2059485

29280000

Characteristics

130

1.45

Red crystals

0.843 g/mL at 20 °C

194 °C

335.43°C (rough estimate)

14 °C

n 20/D 1.374

H2O: slightly soluble ;50% sulfuric acid: 10 mg/mL, clear, colorless

2-8°C

Oral-Rat LD: 500 mg/kg; Abdominal-Mouse LD50: 450 mg/kg

Inflammable in case of open flame, high temperature, oxidant; burning produces toxic nitrogen oxide fumes

Safety Information

II

4.1

UN 3380 4.1/PG 1

3

1-11-22-40-2001/11/22

35-48A-45-36/37-16

MV3325000

F,Xn

Treasury is ventilated, low temperature and dry; stored separately from oxidant

Explosive when mixed with oxidant; explosive due to vibration and impact

Stable when wet, but explosive when dry. May be shock sensitive when dry. Highly flammable. Incompatible with strong oxidizing agents.

P210, P240, P241, P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, P370+P378, P501

H228

|Warning|H228 (93.62%): Flammable solid [Danger Flammable solids]|P210, P240, P241, P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, P370+P378, and P501|Aggregated GHS information provided by 47 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Toxicity

moderately toxic

Drug Information

2,4-dinitro-3,5,6-trideuterophenylhydrazine

(2,4-Dinitrophenyl)hydrazine Use and Manufacturing

Methods of Manufacturing

Hydrazine sulfate was suspended in hot water, potassium acetate was added with stirring, the mixture was boiled for 5 min, cooled to 70°C, and ethanol was added. The solid was filtered and washed with ethanol, and the filtrate was a hydrazine solution. Dissolve 2, 4-dinitrochlorobenzene in ethanol, add the above hydrazine solution, stir to reflux for 1h, cool and filter, wash off the unreacted raw materials with ethanol, wash with hot water, and dry to obtain 2, 4- Dinitrophenylhydrazine (some products can be recovered by concentration of the filtrate), the yield is 81-85%.

Uses

2,4-Dinitrophenylhydrazine is known was Brady's reagent, a substituted hydrazine that is often used for qualitative testing of carbonyl groups associated with aldehydes and ketones.

Hydrazine, (2,4-dinitrophenyl)-: ACTIVE

Computed Properties

Molecular Weight:198.14
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:198.03890469
Monoisotopic Mass:198.03890469
Topological Polar Surface Area:130
Heavy Atom Count:14
Complexity:235
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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