Benzolamide
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Benzolamide
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CAS No:
3368-13-6
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Formula:
C8H8N4O4S3
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Chemical Name:
Benzolamide
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Synonyms:
1,3,4-Thiadiazole-2-sulfonamide,5-[(phenylsulfonyl)amino]-;1,3,4-Thiadiazole-2-sulfonamide,5-benzenesulfonamido-;5-[(Phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide;W 1803;2-Benzenesulfonamide-1,3,4-thiadiazole-5-sulfonamide;2-Benzenesulfonamido-1,3,4-thiadiazole-5-sulfonamide;Benzolamide;CL 11366;5-Benzenesulfonamido-1,3,4-thiadiazole-2-sulfonamide;5-Phenylsulfonamido-1,3,4-thiadiazol-2-sulfonamide
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CAS No:
Description
Selective renal carbonic anhydrase inhibitor. It may also be of use in certain cases of respiratory failure.
Characteristics
177
2.92120
1.746g/cm3
238-241 °C (decomp)
585.9ºC at 760mmHg
308.2ºC
1.689
384.4mg/L(25 ºC)
Drug Information
A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES. (See all compounds classified as Carbonic Anhydrase Inhibitors.)
Benzolamide
Computed Properties
Molecular Weight:320.4
XLogP3:0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:319.97076827
Monoisotopic Mass:319.97076827
Topological Polar Surface Area:177
Heavy Atom Count:19
Complexity:503
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes