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Oxotremorine

Oxotremorine structure

Oxotremorine 

structure
  • CAS No:

    70-22-4

  • Formula:

    C12H18N2O

  • Chemical Name:

    Oxotremorine

  • Synonyms:

    2-Pyrrolidinone,1-[4-(1-pyrrolidinyl)-2-butyn-1-yl]-;2-Pyrrolidinone,1-[4-(1-pyrrolidinyl)-2-butynyl]-;1-[4-(1-Pyrrolidinyl)-2-butyn-1-yl]-2-pyrrolidinone;2′-Oxopyrrolidino-1-pyrrolidino-4-butyne;Oxotremorine;Tremorine,oxo-;1-(2-Oxopyrrolidinyl)-4-pyrrolidinyl-2-butyne;Oxytremorine;1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone;Oxotremorin;NSC 330497

Description

Oxotremorine is a N-alkylpyrrolidine.|A non-hydrolyzed muscarinic agonist used as a research tool.

Oxotremorine Basic Attributes

206.289

206.28

200-728-0

5RY0UWH1JL

330497

DTXSID10220252

Characteristics

23.6

0.58380

1.109g/cm3

<25 °C

152.5 °C

169.1ºC

1.544

Store tigtly sealed and dried; store separately from other chemicals and aromatic substances.

LD50 ipr-rat: 4400 mg/kg TXAPA9 14,67,69

Safety Information

6.1(a)

UN 2810 6.1/PG 1

3

28-34

26-36/37/39-45

T+,C

P260, P264, P270, P280, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, P501

H300

|Danger|H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P280, P301+P310, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, and P501|Aggregated GHS information provided by 127 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Drugs that bind to and activate muscarinic cholinergic receptors (RECEPTORS, MUSCARINIC). Muscarinic agonists are most commonly used when it is desirable to increase smooth muscle tone, especially in the GI tract, urinary bladder and the eye. They may also be used to reduce heart rate. (See all compounds classified as Muscarinic Agonists.)

Oxotremorine

Computed Properties

Molecular Weight:206.28
XLogP3:0.4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:206.141913202
Monoisotopic Mass:206.141913202
Topological Polar Surface Area:23.6
Heavy Atom Count:15
Complexity:293
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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