11α-Hydroxyprogesterone
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11α-Hydroxyprogesterone
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CAS No:
80-75-1
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Formula:
C21H30O3
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Chemical Name:
11α-Hydroxyprogesterone
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Synonyms:
Pregn-4-ene-3,20-dione,11-hydroxy-,(11α)-;Pregn-4-ene-3,20-dione,11α-hydroxy-;Progesterone,11α-hydroxy-;(11α)-11-Hydroxypregn-4-ene-3,20-dione;11α-Hydroxypregn-4-ene-3,20-dione;Pregn-4-en-11α-ol-3,20-dione;U 0384;4-Pregnene-11α-ol-3,20-dione;11α-Hydroxyprogesterone;11-Hydroxyprogesterone;DG 322B;NSC 3350;1942021-77-3
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CAS No:
Description
white to light beige crystalline powder
11alpha-hydroxyprogesterone is a 11alpha-hydroxy steroid that is pregn-4-ene-3,20-dione substituted by a hydroxy group at position 11. It is an 11alpha-hydroxy steroid, a 3-oxo-Delta(4) steroid and a 20-oxo steroid. It derives from a progesterone.
Characteristics
54.4
3.69430
1.15 g/cm3
222 °C
487.4ºC at 760 mmHg
262.7ºC
1.557
116.4mg/L(37 ºC)
Refrigerator
Safety Information
3
24/25
TU5057000
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory.
11α-Hydroxyprogesterone Use and Manufacturing
Progesterone (P755900) metabolite.
Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives [ST0203]
Computed Properties
Molecular Weight:330.5
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:330.21949481
Monoisotopic Mass:330.21949481
Topological Polar Surface Area:54.4
Heavy Atom Count:24
Complexity:621
Defined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes