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Home > Encyclopedia > (14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine

(14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine

(14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine structure

(14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine 

structure
  • CAS No:

    482-22-4

  • Formula:

    C24H27NO3

  • Chemical Name:

    (14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine

  • Synonyms:

    9H-Phenanthro[9,10-b]quinolizine,11,12,13,14,14a,15-hexahydro-2,3,6-trimethoxy-,(14aR)-;Cryptopleurine;9H-Phenanthro[9,10-b]quinolizine,11,12,13,14,14a,15-hexahydro-2,3,6-trimethoxy-,(R)-;(14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine;(-)-Cryptopleurine;(R)-(-)-Cryptopleurine;NSC 19912

  • Categories:

    Organic Chemistry  >  Heterocyclic Ring

Description

ChEBI: An organic heteropentacyclic compound that is (14aR)-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups.


Cryptopleurine is an organic heteropentacyclic compound that is (14aR)-11,12,13,14,14a,15-hexahydro-9H-dibenzo[f,h]pyrido[1,2-b]isoquinoline substituted at positions 2, 3 and 6 by methoxy groups. It has a role as a protein synthesis inhibitor, an antineoplastic agent and an antiviral agent. It is an alkaloid, an organic heteropentacyclic compound, an aromatic ether and an alkaloid antibiotic.

(14aR)-11,12,13,14,14a,15-Hexahydro-2,3,6-trimethoxy-9H-phenanthro[9,10-b]quinolizine Basic Attributes

377.484

377.48

3JZK58H75B

19912

DTXSID3075414

Characteristics

30.9

5.1

195-196 °C

Drug Information

Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)

cryptopleurine

Computed Properties

Molecular Weight:377.5
XLogP3:5.1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:377.19909372
Monoisotopic Mass:377.19909372
Topological Polar Surface Area:30.9
Heavy Atom Count:28
Complexity:542
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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