1,2-Bis(1,1-dimethylethyl) 1,2-benzenedicarboxylate

General procedure: To a 500 ml four-necked flask equipped with a stirring, a thermometer, a distillation apparatus, and a constant pressure dropping funnel, 200 g of toluene and 17.0 g of potassium t-butoxide (0.15 mol) were added, and the mixture was heated to an internal temperature of 100-105 C. 27.8 g (0.1 mol) of To a 500 ml four-necked flask equipped with a stirring, a thermometer, a distillation apparatus, and a constant pressure dropping funnel, 200 g of toluene and 17.0 g of potassium t-butoxide (0.15 mol) were added, and the mixture was heated to an internal temperature of 100-105 C. 27.8 g (0.1 mol) of General procedure: A 200 mL four-necked flask was charged with maleic acid (16.3 g, 140 mmol), toluene (10 mL)Diisopropyl ether (30 mL), Sulfuric acid (0.18 mL) was added, and while maintaining the reaction suspension at 30 C., Normal pressure bubbling of isobutene was carried out for 4 hours.An excess amount of isobutene was discharged to the outside of the flask through a paraffin bubbler. The reaction mixture was washed with a saturated aqueous sodium hydrogen carbonate solution (50 mL × 3 times) and saturated brine (50 mL), dried over magnesium sulfate and the solvent was distilled off under reduced pressure to give maleic acid Di (tert-butyl) ester (23.0 g, 100.8 mmol, yield 72%). The reaction was carried out in the same manner as in except that the reaction temperature was changed from 30 C. to 40 C. As a result, maleic acid Di (tert-butyl) ester(24.1 g, 105.6 mmol, yield 75%).

Molecular Weight:278.34
XLogP3:3.5
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:278.15180918
Monoisotopic Mass:278.15180918
Topological Polar Surface Area:52.6
Heavy Atom Count:20
Complexity:324
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes