 Home > Encyclopedia > Isofraxidin

Isofraxidin

Isofraxidin structure

CAS No:
486-21-5
Formula:
C11H10O5
Chemical Name:
Isofraxidin
Synonyms:
2H-1-Benzopyran-2-one,7-hydroxy-6,8-dimethoxy-;Coumarin,7-hydroxy-6,8-dimethoxy-;Umbelliferone,6,8-dimethoxy-;7-Hydroxy-6,8-dimethoxy-2H-1-benzopyran-2-one;Isofraxidin;6,8-Dimethoxy-7-hydroxycoumarin;Phytodolor;NSC 324637
Categories:
Biochemical Engineering > Plant Extracts

Description

Isofraxidin, a coumarin component from Acanthopanax senticosus, inhibits MMP-7 expression and cell invasion of human hepatoma cells. Isofraxidin inhibits the phosphorylation of ERK1/2 in hepatoma cells[1]. Isofraxidin attenuates the expression of iNOS and COX-2, Isofraxidinalso inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation[2].

Isofraxidin is a hydroxycoumarin.

Isofraxidin Basic Attributes

Molecular Weight：

222.19

Exact Mass：

222.19

UNII：

304915F056

NSC Number：

324637

DSSTox ID：

DTXSID70197557

HScode：

29322090

Characteristics

PSA：

XLogP3：

1.31

Density：

1.4±0.1 g/cm3

Melting Point：

148-149 °C

Boiling Point：

452.1±45.0 °C at 760 mmHg

Flash Point：

183.2±22.2 °C

Refractive Index：

1.588

Water Solubility：

H2O: slightly soluble

Storage Conditions：

-20°C

Vapor Pressure：

8.58E-09mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .

safety instructions：

24/25

RTECS Number：

OY2300000

Marks：

Drug Information

MeSH Entry Terms：

6,8-dimethoxy-7-hydroxy-coumarin

Computed Properties

Molecular Weight:222.19
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:222.05282342
Monoisotopic Mass:222.05282342
Topological Polar Surface Area:65
Heavy Atom Count:16
Complexity:301
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Isofraxidin

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Isofraxidin

CAS No.: 486-21-5

Content: 99.00%

Inquiry
Cuicheng Biomedical Technology Contact Supplier

CN
1 YR

Business licensed Certified factory

Manufactory Supplier of Ginsenoside Rb1,Ginsenoside Rg1,Ginsenoside Re,Ginsenoside CK,Ginsenoside Rg2,Ginsenoside Rg5,Ginsenoside Rg5,Ginsenoside Rh2,Protopanaxatriol,Epmedin C,Icariin,Icaritin,Baohuoside I,Total Ginsenosides,Total Ginsenosides from Ginseng Stems And Leaves,Oridonin,Oleuropein,Curcumin,(20)-Ginsenoside Rg3,(20)-Protopanaxadiol

Isofraxidin

Unit Price: $1000-1200 /G FOB

CAS No.: 486-21-5

Grade: Industrial Grade

Content: 98%

Inquiry

Learn More Other Chemicals

25-Deoxyecdysone

22005-50-1
compoundk

160729-91-9
7-[4-[4-(2-bromophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one

203395-84-0
Moscatilin Formula

108853-14-1
beta-sitosterol sulfate Formula

24815-93-8
Cocoa butter Formula

8002-31-1
(2β,3β,5β,22S)-22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one Structure

26361-67-1
escin IIa Structure

158732-55-9
What is Carvacryl acetate

6380-28-5
What is 13,28-Epoxy-16β-hydroxyolean-11-en-3β-yl 6-deoxy-3-O-(β-D-glucopyranosyl)-β-D-galactopyranoside

64340-44-9

Hot Searches: montelukast dose; fe3o4; cefepine; dimethyl terephthalate drug; magnesium phosphate; iodine chloride

Guide of Isofraxidin

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

Isofraxidin

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.