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Butein

Butein structure

CAS No:
487-52-5
Formula:
C15H12O5
Chemical Name:
Butein
Synonyms:
2-Propen-1-one,1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-,(2E)-;Chalcone,2′,3,4,4′-tetrahydroxy-;Butein;2-Propen-1-one,1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-,(E)-;(2E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)-2-propen-1-one;(E)-1-(2,4-Dihydroxyphenyl)-3-(3,4-hydroxyphenyl)prop-2-en-1-one
Categories:
Natural Products > Chalcones

Description

Butein, a plant polyphenol isolated from Rhus verniciflua, inhibit the activation of protein tyrosine kinase and EGFR. target: EGFR [1]In vitro: 1) Butein inhibited the activation of AKT, extracellular signal-regulated kinase (ERKs) and p38 kinases in the presence of cisplatin.[2] 2) FoxO3a and its downstream molecules play a role in the synergistic effects of butein and cisplatin.[2]3) Butein suppresses cell proliferation and enhances apoptosis in paclitaxel-resistant ovarian cancer cel

Butein Basic Attributes

Molecular Weight：

272.25

Exact Mass：

272.25

EC Number：

207-659-5

HScode：

29145090

Characteristics

PSA：

XLogP3：

2.66

Appearance：

yellow solid

Density：

1.5±0.1 g/cm3

Melting Point：

212-215 °C

Boiling Point：

560.9±50.0 °C at 760 mmHg

Flash Point：

307.1±26.6 °C

Refractive Index：

1.748

Water Solubility：

DMSO: >50 mg/mL

Storage Conditions：

-20°C

Vapor Pressure：

3.46E-13mmHg at 25°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

Butein Use and Manufacturing

Butrin, isobutrin, and butein from medicinal plant Butea monosperma selectively inhibit nuclear factor-κB in activated human mast cells: suppression of tumor necrosis factor-α, interleukin (IL)-6, and IL-8. Anti-inflammatory agent

Recommended Suppliers of Butein

Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
3 YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

butein;

Unit Price: $10 /G EXW

CAS No.: 487-52-5

Grade: Pharmaceutical grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

BUTEIN 99% white powder kanbei

CAS No.: 487-52-5

Grade: Industrial Grade

Content: 99%

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Guide of Butein

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
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Butein

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