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Arecaidine

Arecaidine structure

CAS No:
499-04-7
Formula:
C7H11NO2
Chemical Name:
Arecaidine
Synonyms:
3-Pyridinecarboxylic acid,1,2,5,6-tetrahydro-1-methyl-;Nicotinic acid,1,2,5,6-tetrahydro-1-methyl-;Arecaidine;1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid;N-Methylguvacine;NSC 76017;Arecaine;1-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid;1-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylicacid;1-Methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid;856052-56-7
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

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Description

Crystalline Solid

Solid

Arecaidine is a citraconoyl group.

Arecaidine Basic Attributes

Molecular Weight：

365.44

Exact Mass：

141.17

UNII：

0S8YEV0D4O

NSC Number：

76017

DSSTox ID：

DTXSID60198139

HScode：

2933399090

Characteristics

PSA：

40.54000

XLogP3：

0.77

Appearance：

Solid

Density：

1.2±0.1 g/cm3

Melting Point：

232 °C (decomp)

Boiling Point：

104-112 °C @ Press: 14-16 Torr

Flash Point：

115.1±25.9℃

Refractive Index：

1.524

Storage Conditions：

Store at RT

Vapor Pressure：

0.00245mmHg at 25°C

Toxicity：

sce-mus-ipr 1 g/kg/5D-I CALEDQ 23,189,84

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxide fumes

Safety Information

Storage features：

Warehouse ventilated, low temperature and dry

Drug Information

MeSH Entry Terms：

arecaidine

Arecaidine Use and Manufacturing

A metabolite of Arecoline, a cholinergic agonist.

Computed Properties

Molecular Weight:141.17
XLogP3:-2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:141.078978594
Monoisotopic Mass:141.078978594
Topological Polar Surface Area:40.5
Heavy Atom Count:10
Complexity:174
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Ginseng stimulates the nervous and endocrine systems, improves metabolism, enhances disease resistance and strengthens the heart; rhubarb decoction has a significant inhibitory effect on early exudative edema and late hyperplasia in inflammation.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

A twist of gold
Ingredients	Rhubarb, Gastrodia elata, Betel nut, Ginseng, and Cinnabar.
Indication	Animal experiments have shown that this product can promote the propulsion rate of the small intestine of mice, increase the intestinal volume of mice, inhibit the isolated ileum smooth muscle, increase the defecation frequency and latency of various constipation models of mice, accelerate gastric emptying and increase pepsin secretion in mice, and have a certain protective effect on gastric mucosal damage. In addition, it has certain antitussive, antiasthmatic, expectorant and anti-inflammatory effects.
Specifications	1.2g per bag
Manufacturer	Wuhan Junan Pharmaceutical Co., Ltd.

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ARECAIDINE BUT-2-YNYL ESTER TOSYLATE

CAS No.: 499-04-7

Grade: Industrial Grade

Content: 99%

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CAS No.: 499-04-7

Grade: Industrial Grade

Content: 99%

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