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Valnoctamide

Valnoctamide structure

Valnoctamide 

structure
  • CAS No:

    4171-13-5

  • Formula:

    C8H17NO

  • Chemical Name:

    Valnoctamide

  • Synonyms:

    Pentanamide,2-ethyl-3-methyl-;Valeramide,2-ethyl-3-methyl-;2-Ethyl-3-methylpentanamide;McN X 181;Axiquel;2-Ethyl-3-methylvaleramide;Nirvanil;Valmethamide;Valnoctamide;NSC 32363;NSC 34092

Description

Valnoctamide (Valmethamide), a derivative of valproate, suppresses benzodiazepine-refractory status epilepticus. Valnoctamide (Valmethamide) acts directly on GABAA receptors[1].


Valnoctamide is a fatty amide.|Valnoctamide has been used in trials studying the treatment of Mania and Schizoaffective Disorder, Manic Type.

Valnoctamide Basic Attributes

143.23

143.23

224-033-7

3O25NRX9YG

34092|32363

N - Nervous system

2924199090

Characteristics

43.1

2.24430

0.883g/cm3

113.75 °C

274.4ºC at 760mmHg

119.8ºC

1.438

8.70g/L(temperature not stated)

LD50 oral in rat: 760mg/kg

Safety Information

NONH for all modes of transport

3

YV5950000

Xn

P264, P270, P301+P312, P330, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

2-ethyl-3-methylpentamide

Valnoctamide Use and Manufacturing

Isomer of Valpromide. Anxiolytic

Computed Properties

Molecular Weight:143.23
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:143.131014166
Monoisotopic Mass:143.131014166
Topological Polar Surface Area:43.1
Heavy Atom Count:10
Complexity:112
Undefined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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