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2′,7′-Dichlorodihydrofluorescein diacetate

2′,7′-Dichlorodihydrofluorescein diacetate structure

CAS No:
4091-99-0
Formula:
C24H16Cl2O7
Chemical Name:
2′,7′-Dichlorodihydrofluorescein diacetate
Synonyms:
Benzoic acid,2-[3,6-bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]-;Benzoic acid,o-(2,7-dichloro-3,6-dihydroxyxanthen-9-yl)-,diacetate;2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic acid;2′,7′-Dichlorodihydrofluorescein diacetate;DCFH;H2DCFDA;DCFH-DA;2-(3,6-Diacetoxy-2,7-dichloro-9H-xanthen-9-yl)benzoic acid

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Description

H2DCFDA is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS).

2′,7′-Dichlorodihydrofluorescein diacetate Basic Attributes

Molecular Weight：

487.29

Exact Mass：

487.29

DSSTox ID：

DTXSID9063293

HScode：

2932999099

Characteristics

PSA：

99.1

XLogP3：

5.2

Density：

1.5±0.1 g/cm3

Melting Point：

209-210ºC(lit.)

Boiling Point：

593.5°C at 760 mmHg

Flash Point：

312.7±30.1 °C

Refractive Index：

1.635

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

S22-S24/25

Marks：

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

H315-H319-H335

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

2',7'-dichlorodihydrofluorescein diacetate

2′,7′-Dichlorodihydrofluorescein diacetate Use and Manufacturing

Uses

Cell-permeable fluorogenic probe used to measure reactive oxygen species (ROS) within cells by detection of enzymatically formed hydrogen peroxide. 2',7'-Dichlorodihydrofluorescein as a cell-permeable non-fluorescent probe. It is de-esterified intracellularly and turns to highly fluorescent 2’7’dichlorofluorescein upon oxidation.

Manufacturing Info：

Benzoic acid, 2-[3,6-bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]-: ACTIVE

Computed Properties

Molecular Weight:487.3
XLogP3:5.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:486.0273082
Monoisotopic Mass:486.0273082
Topological Polar Surface Area:99.1
Heavy Atom Count:33
Complexity:717
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2′,7′-Dichlorodihydrofluorescein diacetate

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
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2,7-Dichlorodihydrofluorescein diacetate

CAS No.: 4091-99-0

Content: 99.00%

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Creative Enzymes Contact Supplier

US
6 YRS

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Manufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates

2',7'-Dichlorofluorescin diacetate

CAS No.: 4091-99-0

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Guide of 2′,7′-Dichlorodihydrofluorescein diacetate

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
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2′,7′-Dichlorodihydrofluorescein diacetate

SDS

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