Phenylmercury chloride

313.15

313.97900

202-865-1

DTXSID4042129

White satiny leaflets

0

1.54820

250-252 °C

soluble in benzene, ether, pyridine.Very slightly soluble in water

Poison room

Oral-rat LD50: 60 mg/kg

Thermal decomposition of toxic chloride and mercury-containing gas

II

6.1

UN 2026 6.1/PG 3

3

26/27/28-33-50/53

13-28-36-45-60-61

OW1400000

T+,N

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Alkyl mercurials are very stable relative to aryl mercurials such as phenylmercury, which is rapidly broken down into Hg2+ in animals and the soil. /Mercurials/

P260-P273-P280-P301 + P310 + P330-P302 + P352 + P310-P304 + P340 + P310

H300 + H310 + H330-H373-H410

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

|Danger|H300+H310+H330 (12.5%): Fatal if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]|P260, P262, P264, P270, P271, P273, P280, P284, P301+P310, P302+P350, P304+P340, P310, P314, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, and P501|Aggregated GHS information provided by 8 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Health: Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Phenylmercuric compound, NOS/|/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Fire or Explosion: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways. /Phenylmercuric compound, NOS/|/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Public Safety: CALL Emergency Response Telephone Number ... . As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at lease 25 meters (75 feet) for solids. Keep unauthorized personnel away. Stay upwind. Keep out of low areas. /Phenylmercuric compound, NOS/|/GUIDE 151: SUBSTANCES - TOXIC (NON-COMBUSTIBLE)/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA). Wear chemical protective clothing that is specifically recommended by the manufacturer. It may provide little or no thermal protection. Structural firefighters' protective clothing provides limited protection in fire situations ONLY; it is not effective in spill situations where direct contact with the substance is possible. /Phenylmercuric compound, NOS/|For more DOT Emergency Guidelines (Complete) data for PHENYLMERCURIC CHLORIDE (8 total), please visit the HSDB record page.

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./|The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.|The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Exposure of the skin to a concentrated solution of phenylmercury cmpd may cause chemical burns with blistering. /Phenylmercury cmpd/

Listed as a hazardous air pollutant (HAP) generally known or suspected to cause serious health problems. The Clean Air Act, as amended in 1990, directs EPA to set standards requiring major sources to sharply reduce routine emissions of toxic pollutants. EPA is required to establish and phase in specific performance based standards for all air emission sources that emit one or more of the listed pollutants. Phenylmercuric chloride is included on this list.

D009; Mercury. A waste containing mercury may or may not be characterized as a hazardous waste following testing by the Toxicity Characteristic Leaching Procedure as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations. /Mercury/

highly toxic

LD50 Mouse ip 8 mg/kg /PhHg/

FUNGICIDAL ACTIVITY OF /PHENYLMERCURIC/ ... CMPD /NOT/ DECREASED MARKEDLY AFTER 52 HR OF LIGHT EXPOSURE ... FOLLOWING CMPD BARELY DECOMPOSED AFTER EQUIV OF 7 DAYS ULTRAVIOLET LIGHT: ... PHENYLMERCURIC CHLORIDE ... .

... A large fraction of the /phenylmercury/ spray residue was found in the soil 30-50 days after application; the rest of the Hg was lost by vaporization (either as the organic cmpd or after conversion to Hg metal) or by migration to lower soil horizons since water containing organic cmpd from decomposing vegetable matter can leach adsorbed Hg. /Phenylmercury spray/

Prior to 1991, phenylmercuric compounds were used as biocides in 25-30% of interior and exterior latex paint; however, this use of mercury was voluntarily discontinued for interior paint in 1990 and for exterior paint in 1991(1). The use of phenylmercury resulted in the exposure of house painters and residents to mercury vapors in the homes where interior and exterior latex paint was applied(1). Although the use of mercury biocides in latex paint has been discontinued, it is possible that people who use old latex paint in their homes will be exposed to mercury for a considerable time(1). Furthermore, although phenylmercury use in exterior latex paints was discontinued in 1991, paint companies were allowed to continue to produce and sell paint containing phenylmercury until the existing stocks of phenylmercury were exhausted(1).

PHARMACEUTIC AID (ANTIMICROBIAL AGENT) /FORMER USE/|ANTISEPTIC AGENT /FORMER USE/

PHENYLMERCURIC CHLORIDE AT DOSAGE OF 10 MG HG/KG WAS ADMIN SC TO 7 WK OLD RATS. HIGHEST CONCN FOUND IN KIDNEY & RAPID DECR IN CONCN IN ORGANS OTHER THAN KIDNEY WAS OBSERVED. ACCUM OF MERCURY IN ORGANS & TISSUES WAS HIGHER & LONGER-LASTING WHEN ALKYL MERCURY ADMIN.|Phenylmercury absorbed through the skin from contaminated diapers affected urinary excretion in infants in Buenos Aires. The effects were reversible and quantitatively related to the concn of urinary Hg. Excretion of gamma-glutamyl transpeptidase, an enzyme in the brush-borders of renal tubular cells, increased in a dose-dependent manner when Hg excretion exceeded a threshold value. Urine volume also increased but at a higher threshold with respect to Hg. The results support the threshold concept of the systemic toxicity of metals. Gamma-glutamyl transpeptidase is a useful and sensitive marker for preclinical effects of mercury. /Phenylmercury cmpd/|INORGANIC MERCURIAL SALTS AND ... PHENYL MERCURIC SALTS ARE SIMILAR IN MANY RESPECTS. ... A LARGER PORTION OF MERCURY IS ABSORBED AFTER ORAL ADMINISTRATION OF PHENYL MERCURIC SALTS. ... VIRTUALLY ALL ... MERCURY IN ... KIDNEYS IS PRESENT AS INORGANIC MERCURY FOLLOWING DOSES OF PHENYL MERCURY ... /PHENYL MERCURIC SALTS/|PHENYL MERCURY EVIDENTLY PENETRATES CELL MEMBRANES MORE EASILY THAN HG2+. ... ABOUT 90% OF PHENYL MERCURY IN BLOOD IS FOUND IN RED CELLS. HOWEVER NEITHER PHENYL MERCURY NOR METHOXYETHYL MERCURY IS TRANSFERRED THROUGH BLOOD-BRAIN BARRIER OR PLACENTAL BARRIER TO LARGER EXTENT THAN HG2+. /PHENYL MERCURY/|For more Absorption, Distribution and Excretion (Complete) data for PHENYLMERCURIC CHLORIDE (8 total), please visit the HSDB record page.

FROM A CELL-FREE EXTRACT OF MERCURY-RESISTANT PSEUDOMONAS, AN ENZYME WAS OBTAINED WHICH CATALYZED REDUCTION OF MERCURY IN ... INORG MERCURIALS TO METALLIC MERCURY. A PROSTHETIC GROUP OF THE ENZYME WAS IDENTIFIED AS FAD (FLAVINE ADENINE DINUCLEOTIDE). /INORGANIC MERCURIALS/

Phenylmercury absorbed through the skin from contaminated diapers affected urinary excretion in infants in Buenos Aires. The effects were reversible and quantitatively related to the concn of urinary Hg. /Phenylmercury cmpd/

phenylmercuric chloride

OTHER NAME: STOPSPOT (PRODUCTION DISCONTINUED BY ICI AUSTRALIA LTD)