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Dibenzepin

Dibenzepin structure

Dibenzepin 

structure
  • CAS No:

    4498-32-2

  • Formula:

    C18H21N3O

  • Chemical Name:

    Dibenzepin

  • Synonyms:

    11H-Dibenzo[b,e][1,4]diazepin-11-one,10-[2-(dimethylamino)ethyl]-5,10-dihydro-5-methyl-;10-[2-(Dimethylamino)ethyl]-5,10-dihydro-5-methyl-11H-dibenzo[b,e][1,4]diazepin-11-one;Dibenzepin;Dibenzepine;HF 1927;Victoril

Description

Crystalline Solid


5-[2-(dimethylamino)ethyl]-11-methyl-6-benzo[b][1,4]benzodiazepinone is a dibenzodiazepine.|Dibenzepin is approved for use in Europe.

Dibenzepin Basic Attributes

295.386

295.38

510SJZ1Y6L

DTXSID7022916

N - Nervous system

2933990090

Characteristics

26.8

2.61700

1.134g/cm3

116-117 °C

185 °C @ Press: 0.01 Torr

194.9ºC

1.592

Refrigerator

Safety Information

III

6.1(b)

UN 3249

Drug Information

Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system. (See all compounds classified as Antidepressive Agents, Tricyclic.)

dibenzepin

Dibenzepin Use and Manufacturing

Uses

Antidepressant

Pharmaceuticals

Computed Properties

Molecular Weight:295.4
XLogP3:2.7
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:295.168462302
Monoisotopic Mass:295.168462302
Topological Polar Surface Area:26.8
Heavy Atom Count:22
Complexity:398
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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