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Oxyphenisatin

Oxyphenisatin structure

CAS No:
125-13-3
Formula:
C20H15NO3
Chemical Name:
Oxyphenisatin
Synonyms:
2H-Indol-2-one,1,3-dihydro-3,3-bis(4-hydroxyphenyl)-;2-Indolinone,3,3-bis(p-hydroxyphenyl)-;Oxindole,3,3-bis(p-hydroxyphenyl)-;1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-2H-indol-2-one;3,3-Bis(p-hydroxyphenyl)-2-indolinone;3,3-Bis(p-hydroxyphenyl)oxindole;3,3-Bis(4-hydroxyphenyl)oxindole;Diphenolisatin;Neodrast;Oxyphenisatin;Oxyphenisatine;Phenolisatin;Veripaque;Lavema;4,4′-Dihydroxydiphenylisatin;Isolax;Isatinbisphenol;Hoscolax;Normalax;Propellax;Recolon;NSC 59814;3,3-Bis(4-hydroxyphenyl)-1,3-dihydroindol-2-one;3,3-Bis(4-hydroxyphenyl)-1H-indol-2-one
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

Description

Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-drug of oxyphenisatin with anticancer activity.

Oxyphenisatine is a member of indoles.|A laxative that undergoes enterohepatic circulation. It may cause jaundice.

Oxyphenisatin Basic Attributes

Molecular Weight：

317.34

Exact Mass：

317.34

EC Number：

204-728-1

UNII：

3BT0VQG2GQ

NSC Number：

59814

DSSTox ID：

DTXSID5044528

ATC Code：

A - Alimentary tract and metabolism

HScode：

2933790090

Characteristics

PSA：

69.6

XLogP3：

3.52230

Density：

1.352±0.06 g/cm3(Predicted)

Melting Point：

260-261 °C

Boiling Point：

562.9±50.0 °C(Predicted)

Flash Point：

294.2ºC

Refractive Index：

1.691

Vapor Pressure：

2.82E-13mmHg at 25°C

Safety Information

Precautionary statement(s)：

P264, P270, P301+P310, P321, P330, P405, P501

Hazard Statements：

H301

GHS Classification：

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P301+P310, P321, P330, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH：

Agents that are used to stimulate evacuation of the bowels. (See all compounds classified as Cathartics.)

MeSH Entry Terms：

Acetate, Oxyphenisatin

Oxyphenisatin Use and Manufacturing

An intermediate of triacetin.

Computed Properties

Molecular Weight:317.3
XLogP3:3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:317.10519334
Monoisotopic Mass:317.10519334
Topological Polar Surface Area:69.6
Heavy Atom Count:24
Complexity:442
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes