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Home > Encyclopedia > 1,6-Bismaleimidohexane

1,6-Bismaleimidohexane

1,6-Bismaleimidohexane structure

1,6-Bismaleimidohexane 

structure
  • CAS No:

    4856-87-5

  • Formula:

    C14H16N2O4

  • Chemical Name:

    1,6-Bismaleimidohexane

  • Synonyms:

    1H-Pyrrole-2,5-dione,1,1′-(1,6-hexanediyl)bis-;Maleimide,N,N′-hexamethylenedi-;1,1′-(1,6-Hexanediyl)bis[1H-pyrrole-2,5-dione];N,N′-Hexamethylenedimaleimide;1,6-Dimaleimidohexane;N,N′-Hexamethylenebis[maleimide];1,6-Hexamethylenebis[maleimide];1,6-Bismaleimidohexane;NSC 12818;1,6-Maleimidohexane;GMBMI;1,6-Hexanediylbismaleimide;1,6-Bismaleimidehexane;Hexamethylenediamine bismaleimide;GP 207R;BMH Crosslinker;1,6-BMH;1-[6-(2,5-Dioxopyrrol-1-yl)hexyl]pyrrole-2,5-dione;1,1′-hexane-1,6-diylbis(1H-pyrrole-2,5-dione);1,1′-(Hexane-1,6-diyl)bis(1H-pyrrole-2,5-dione);1333231-70-1

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

Off-White Solid

1,6-Bismaleimidohexane Basic Attributes

276.29

276.29

225-449-1

12818

DTXSID3073343

29251900

Characteristics

74.8

1.68

1.3±0.1 g/cm3

136-141 °C

465.7±28.0 °C at 760 mmHg

218.1±16.4 °C

1.572

soluble in chloroform.

0-6°C

Safety Information

ON5520000

P261, P264, P272, P280, P302+P352, P305+P351+P338, P312, P321, P322, P332+P313, P333+P313, P337+P313, P361, P362, P363, P405, P501

H311

|Danger|H311 (87.5%): Toxic in contact with skin [Danger Acute toxicity, dermal]|P261, P264, P272, P280, P302+P352, P305+P351+P338, P312, P321, P322, P332+P313, P333+P313, P337+P313, P361, P362, P363, P405, and P501|Aggregated GHS information provided by 16 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

1,6-bismaleimidohexane

1,6-Bismaleimidohexane Use and Manufacturing

A sulfhydryl reactive homobifunctional crosslinking reagent. Under mild conditions, will permit irreversible cross-linking of sulfhydral containing compounds at a pH range of 6.5 to 7.5.Spacer Arm: 16.1 Angstroms

Computed Properties

Molecular Weight:276.29
XLogP3:0.2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:276.11100700
Monoisotopic Mass:276.11100700
Topological Polar Surface Area:74.8
Heavy Atom Count:20
Complexity:425
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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