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Sulfoxone sodium

Sulfoxone sodium structure

CAS No:
144-75-2
Formula:
C14H16N2O6S3.2Na
Chemical Name:
Sulfoxone sodium
Synonyms:
Methanesulfinic acid,1,1′-[sulfonylbis(4,1-phenyleneimino)]bis-,sodium salt (1:2);Methanesulfinic acid,[sulfonylbis(p-phenyleneimino)]di-,disodium salt;Methanesulfinic acid,[sulfonylbis(4,1-phenyleneimino)]bis-,disodium salt;Aldapsone;Aldesulfone sodium;Diamidin;Diasone;Diasone sodium;Diazon;Disodium formaldehydesulfoxylate-diaminodiphenyl sulfone;Novotrone;Sodium sulfoxone;[Sulfonylbis(p-phenyleneimino)]dimethanesulfinic acid,disodium salt;Sulfoxone sodium;Benzenamine,4,4′-sulfonylbis-,bis(sodium formaldehydesulfonylate);Sodium aldesulphone;Diason;NSC 27222;1081827-95-3
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Description

Sulfoxone Sodium is a sodium salt form of sulfoxone, a water-soluble sulfonamide antibiotic used in the treatment of leprosy.

Sulfoxone sodium Basic Attributes

Molecular Weight：

448.44500

Exact Mass：

447.98100

UNII：

57OWB0Q221

DSSTox ID：

DTXSID9023623

NCI Thesaurus Code：

C66574

ATC Code：

J - Antiinfectives for systemic use

HScode：

2930909090

Characteristics

PSA：

185.26000

XLogP3：

3.97460

Melting Point：

263-265 °C (decomp)

Boiling Point：

857.3ºC at 760 mmHg

Flash Point：

472.3ºC

Safety Information

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents.

Drug Information

MeSH Entry Terms：

aldesulfon sodium

Sulfoxone sodium Use and Manufacturing

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:448.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:6
Exact Mass:447.98093826
Monoisotopic Mass:447.98093826
Topological Polar Surface Area:185
Heavy Atom Count:27
Complexity:509
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes