Fluorescein Sodium
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Fluorescein Sodium
structure -
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CAS No:
518-47-8
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Formula:
C20H13NaO5
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Chemical Name:
Fluorescein Sodium
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Synonyms:
9-(o-carboxyphenyl)-6-hydroxy-3h-xanthen-3-one,disodiumsalt;9’-(9h)xanthen)-3-one,3’,6’-dihydroxy-spiro(isobenzofuran-1(3hdisodiums;9’-[9h]xanthen]-3-one,3’,6’-dihydroxy-spiro[isobenzofuran-1(3hdisodiumsal;9-o-carboxyphenyl-6-hydroxy-3-isoxanthone,disodiumsalt;abcoluraninepowders&liquids;aizenuranine;c.i.45350disodiumsalt;c.i.45350sodiumsalt
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CAS No:
Description
Orange-red powder; odorless. Hygroscopic,soluble in water; sparingly soluble inalcohol.
Fluorescein sodium is an orange-red to dark red powder. Water-soluble form of fluorescein. Odorless and almost tasteless. pH (5% solution) 7.8. May be sensitive to prolonged exposure to light and to heat.
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Human systemic effects by intravenous route: arrhythmias, eye hemorrhage, nausea or vomiting. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Na2O.
Fluorescein Sodium Basic Attributes
356.31
376.03200
3833041
208-253-0
TSCA listed
Rust-orange
32041200
Characteristics
491nm, 493.5nm, 490nm
81.65000
4.54220
Fluorescein, disodium salt is an orange-red to dark red powder. Water-soluble form of fluorescein. Odorless and almost tasteless. pH (5% solution) 7.8. May be sensitive to prolonged exposure to light and to heat.
0.579[at 20℃]
320 °C
620.8ºC at 760 mmHg
232.6ºC
500 g/L (20 ºC)
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
2.133hPa
LD50 in mice, rats (mg/kg): 4738, 6721 orally (Yankel, Loux)
Odorless
8.3 (10g/l, H2O, 20℃)
2.2, 4.4, 6.7(at 25℃)
3.5×1010mol/(m3Pa) at 25℃, HSDB (2015)
Hygroscopic. Water soluble.
Fluorescein disodium salt is incompatible with strong oxidizers. Also incompatible with acids, acid salts and salts of heavy metals .
Store at +5°C to +30°C.
Safety Information
NONH for all modes of transport
1
Xi
22-24/25-37/39-26-36/37/39-27
LM5425000
Xi
Stable.
36-36/37/38
Flash point data for Fluorescein disodium salt are not available; however, Fluorescein disodium salt is probably combustible.
Fluorescein Sodium Use and Manufacturing
A sodium salt of fluorescein Same as fluorescein.
Fluorescein sodium salt is a sodium salt of fluorescein. It can also be used in technical or engineered material use in-situ photochemical fabrication of transition metal-promoted amorphous molybdenum sulfide catalysts for enhanced photosensitized hydrogen evolution. Dyes and metabolites, Environmental Testing
In examining subterranean waters. Serves to ascertain source of springs, connections between streams and sea, determining approx vol of water delivered by a spring, detecting source of contamination of drinking water, infiltration of soil with waste waters of factories. In externally applied drugs and cosmetics. Analytical reagent (protein label). Clinical reagent (immuno-histological stain, immuno-fluorescent label).
Drug Function and Efficacy
Extract from the above information
Registered Holders
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BIOPHORE INDIA PHARMACEUTICALS PVT LTD
Active
United States
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APICORE LLC
Active
United States
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ORxes Biopharmaceuticals (Shenyang) Co., Ltd.
Active
China
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