Sulochrin
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Sulochrin
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CAS No:
519-57-3
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Formula:
C17H16O7
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Chemical Name:
Sulochrin
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Synonyms:
Benzoic acid,2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxy-,methyl ester;m-Anisic acid,5-hydroxy-2-(4-methyl-γ-resorcyloyl)-,methyl ester;Sulochrin
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CAS No:
Description
Sulochrin is a benzophenone that is the methyl ester of 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoic acid. It has a role as a metabolite. It is a member of benzophenones, a carboxylic ester and a member of phenols. It derives from a demethylsulochrin. It is a conjugate acid of a sulochrin(1-).
Characteristics
113
2.9
1.378±0.06 g/cm3(Predicted)
242-248 °C (decomp)
576.3ºC at 760 mmHg
212.6ºC
1.622
2-8ºC
Sulochrin Use and Manufacturing
Sulochrin is a fungal metabolite isolated from a number of Aspergillus and Penicillium sp.. An anti-angiogenic agent, sulochrin inhibits VEGF leading to inhibition of capillary-like tube formation of human umbilical vein endothelial cells. Sulochrin also inhibits eosinophil activation and chemotaxis.
Computed Properties
Molecular Weight:332.3
XLogP3:2.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:332.08960285
Monoisotopic Mass:332.08960285
Topological Polar Surface Area:113
Heavy Atom Count:24
Complexity:454
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes