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Pheniprazine

Pheniprazine structure

CAS No:
55-52-7
Formula:
C9H14N2
Chemical Name:
Pheniprazine
Synonyms:
Hydrazine,(1-methyl-2-phenylethyl)-;Hydrazine,(α-methylphenethyl)-;(1-Methyl-2-phenylethyl)hydrazine;Catron;Dicatron;2-Hydrazino-1-phenylpropane;(α-Methylphenethyl)hydrazine;Pheniprazine;Phenizine;1-Phenyl-2-hydrazinopropane;(β-Phenylisopropyl)hydrazine;PIH;(1-Phenylpropan-2-yl)hydrazine;1-(1-Methyl-2-phenylethyl)hydrazine;1-(1-Phenylpropan-2-yl)hydrazine;52031-11-5
Categories:
Organic Chemistry > Hydrazine or Hydroxylamine Derivatives

Description

Pheniprazine is a member of amphetamines.|Pheniprazine is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was used as an antidepressant in the 1960s. In addition, it was used for the treatment of other conditions, such as angina pectoris and schizophrenia. Pheniprazine was withdrawn by its manufacturer due to its ability to cause toxicity in the liver and its ability to cause optic neuritis.

Pheniprazine Basic Attributes

Molecular Weight：

150.225

Exact Mass：

150.22

EC Number：

200-236-6

DSSTox ID：

DTXSID6043838

HScode：

2928000090

Characteristics

PSA：

38.05000

XLogP3：

2.17210

Density：

0.99g/cm3

Melting Point：

<25 °C

Boiling Point：

136.5 °C

Flash Point：

148ºC

Refractive Index：

1.539

Toxicity：

LD50 orl-rat: 34 mg/kg 27ZQAG -,353,72

Drug Information

Drug Indication：

For the treatment of depression, schizophrenia, and angina pectoris.

MeSH Entry Terms：

beta-phenylisopropylhydrazine

Computed Properties

Molecular Weight:150.22
XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:150.115698455
Monoisotopic Mass:150.115698455
Topological Polar Surface Area:38
Heavy Atom Count:11
Complexity:97.7
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes