γ-Oxo-8-fluoranthenebutanoic acid

302.329

302.32

208-279-2

UZ5LMI200P

DTXSID3023055

FINE PLATELETS FROM DIOXANE + ETHANOL

2918300090

54.4

4.53470

1.367g/cm3

195 °C

574.2ºC at 760mmHg

315.1ºC

1.786

SOL IN METHANOL, ETHANOL, AQ SOLN OF SODIUM CARBONATE

UN 2811 6.1/PG 3

3

R25

28-45

DV1761000

T

Cholagogues and Choleretics|DRUG THAT STIMULATES LIVER TO INCR OUTPUT OF BILE IS CALLED CHOLERETIC. DRUG THAT STIMULATES LIVER TO INCR OUTPUT OF BILE OF LOW SPECIFIC GRAVITY IS CALLED HYDROCHOLERETIC. /CHOLERETIC AGENTS/|HYDROCHOLERETIC AGENT WHICH HAS BEEN PROPOSED FOR MGMNT OF CHRONIC INFLAMMATION OF GALLBLADDER & BILE DUCTS & IN PREVENTION OF BILIARY CALCULI.|BILE SALTS OR UNNATURAL CHOLAGOGUES... THEY ARE USED TO REPLACE ENDOGENOUS BILE SALTS WHEN DEFICIENCY EXISTS. THEY CAN BE GIVEN TO PROMOTE FLOW OF BILE OR TO INCR INTRABILIARY PRESSURE. /BILE SALTS OR UNNATURAL CHOLAGOGUES/|For more Therapeutic Uses (Complete) data for FLORANTYRONE (7 total), please visit the HSDB record page.

IT IS PROMOTED FOR USE IN GALLBLADDER DYSFUNCTION, BILIARY DYSKINESIA, & OTHER VAGUE SYMPTOMS, AS WELL AS TO PREVENT ENCRUSTATION OF T-TUBE. NO SATISFACTORY CONTROLLED STUDIES TO SUBSTANTIATE THESE USES ARE AVAILABLE, & IT IS CONCLUDED THAT FLORANTYRONE IS NOT USEFUL THERAPEUTICALLY.|FLORANTYRONE IS CONTRAINDICATED IN PT WITH CHOLECYSTITIS, HEPATITIS OR GALLSTONES.

ALTHOUGH FLORANTYRONE IS PROMOTED AS HYDROCHOLERETIC, OUTPUTS OF BILE & BILE ACIDS ARE INCR PROPORTIONATELY; AT BEST, ITS ACTION IS MILD COMPARED TO THAT OF BILE SALTS.

ALLERGIC REACTIONS, NAUSEA, VOMITING, & DIARRHEA HAVE OCCURRED. CHANGES IN RESULTS OF SOME LIVER FUNCTION TESTS ALSO HAVE BEEN REPORTED.

florantyrone

...IS MARKETED AS 250-MG TABLETS...