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Felypressin

pharmaceutical raw materials
Felypressin structure

Felypressin 

structure
  • CAS No:

    56-59-7

  • Formula:

    C46H65N13O11S2

  • Chemical Name:

    Felypressin

  • Synonyms:

    PLV-2;FELYPRESSIN;Octapressin;Phelypressin;FelypressinAcetate;[PHE2,LYS8]-VASOPRESSIN;M.W.1040.22C46H65N13O11S2;2-(phenylalanine)-8-lyinevasopression;2-(Phenylalanine)-8-lysinevasopressin;(2-L-Phenylalanine)-8-lysinevasopressin

  • Categories:

    Biochemical Engineering  >  Polypeptide

Description

Felypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures.


A synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity.

Felypressin Basic Attributes

1040.22

1039.436768

200-282-7

DTXSID6048599

Characteristics

455.92000

-5.00

1.3±0.1 g/cm3

254-257 °C

1571.3±65.0 °C at 760 mmHg

904.1±34.3 °C

1.574

Safety Information

NONH for all modes of transport

3

R36/37/38:Irritating to eyes, respiratory system and skin .

S24/25

Xi

Drug Information

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)

Felypressin

Felypressin Use and Manufacturing

Felypressin(Octapressin) is a vasopressin 1 agonist and a peptide containing eight amino acids including cystine. Felypressin is used as a vasoconstrictor.

Computed Properties

Molecular Weight:1040.2
XLogP3:-3.5
Hydrogen Bond Donor Count:12
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:19
Exact Mass:1039.43679229
Monoisotopic Mass:1039.43679229
Topological Polar Surface Area:456
Heavy Atom Count:72
Complexity:1920
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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