Felypressin
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Felypressin
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CAS No:
56-59-7
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Formula:
C46H65N13O11S2
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Chemical Name:
Felypressin
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Synonyms:
PLV-2;FELYPRESSIN;Octapressin;Phelypressin;FelypressinAcetate;[PHE2,LYS8]-VASOPRESSIN;M.W.1040.22C46H65N13O11S2;2-(phenylalanine)-8-lyinevasopression;2-(Phenylalanine)-8-lysinevasopressin;(2-L-Phenylalanine)-8-lysinevasopressin
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CAS No:
Description
Felypressin is a Vasopressin 1 agonist, and will thus have effects at all Arginine vasopressin receptor 1As.target: Vasopressin 1 agonist;Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures.Felypressin has been widely added to local anesthetic solutions to increase the duration of the anesthetic effect and reduce the risk of toxicity during dental procedures.
A synthetic analog of LYPRESSIN with a PHENYLALANINE substitution at residue 2. Felypressin is a vasoconstrictor with reduced antidiuretic activity.
Characteristics
455.92000
-5.00
1.3±0.1 g/cm3
254-257 °C
1571.3±65.0 °C at 760 mmHg
904.1±34.3 °C
1.574
Safety Information
NONH for all modes of transport
3
R36/37/38:Irritating to eyes, respiratory system and skin .
S24/25
Xi
Drug Information
Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)
Felypressin
Felypressin Use and Manufacturing
Felypressin(Octapressin) is a vasopressin 1 agonist and a peptide containing eight amino acids including cystine. Felypressin is used as a vasoconstrictor.
Computed Properties
Molecular Weight:1040.2
XLogP3:-3.5
Hydrogen Bond Donor Count:12
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:19
Exact Mass:1039.43679229
Monoisotopic Mass:1039.43679229
Topological Polar Surface Area:456
Heavy Atom Count:72
Complexity:1920
Undefined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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