Karanjin
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Karanjin
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CAS No:
521-88-0
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Formula:
C18H12O4
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Chemical Name:
Karanjin
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Synonyms:
4H-Furo[2,3-h]-1-benzopyran-4-one,3-methoxy-2-phenyl-;Karanjin;3-Methoxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one;NSC 335755;Derisom;3-Methoxy-2-phenylfuro[2,3-h]chromen-4-one
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CAS No:
Description
Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].
Karanjin is an extended flavonoid.
Characteristics
48.7
3.29
1.4±0.1 g/cm3
158 °C
463.0±45.0 °C at 760 mmHg
233.8±28.7 °C
1.678
160.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Safety Information
S22-S24/25
DX1500000
P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501
H302
Karanjin Use and Manufacturing
Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]
Computed Properties
Molecular Weight:292.3
XLogP3:3.8
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:292.07355886
Monoisotopic Mass:292.07355886
Topological Polar Surface Area:48.7
Heavy Atom Count:22
Complexity:478
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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