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Karanjin

Karanjin structure

Karanjin 

structure
  • CAS No:

    521-88-0

  • Formula:

    C18H12O4

  • Chemical Name:

    Karanjin

  • Synonyms:

    4H-Furo[2,3-h]-1-benzopyran-4-one,3-methoxy-2-phenyl-;Karanjin;3-Methoxy-2-phenyl-4H-furo[2,3-h]-1-benzopyran-4-one;NSC 335755;Derisom;3-Methoxy-2-phenylfuro[2,3-h]chromen-4-one

  • Categories:

    Biochemical Engineering  >  Plant Extracts

Description

Karanjin is a major active furanoflavonol constituent of Fordia cauliflora. Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis[1][2].


Karanjin is an extended flavonoid.

Karanjin Basic Attributes

292.29

292.29

208-319-9

WV7IM0I02M

335755

DTXSID20200106

2932999099

Characteristics

48.7

3.29

1.4±0.1 g/cm3

158 °C

463.0±45.0 °C at 760 mmHg

233.8±28.7 °C

1.678

160.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Safety Information

S22-S24/25

DX1500000

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H302

Drug Information

3-methoxy-2-phenyl-4H-furo(2,3-h)-1-benzopyran-4-one

Karanjin Use and Manufacturing

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:292.3
XLogP3:3.8
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:292.07355886
Monoisotopic Mass:292.07355886
Topological Polar Surface Area:48.7
Heavy Atom Count:22
Complexity:478
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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