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Phenobarbital sodium

Phenobarbital sodium structure

CAS No:
57-30-7
Formula:
C12H12N2O3.Na
Chemical Name:
Phenobarbital sodium
Synonyms:
2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-phenyl-,sodium salt (1:1);Barbituric acid,5-ethyl-5-phenyl-,sodium salt;2,4,6(1H,3H,5H)-Pyrimidinetrione,5-ethyl-5-phenyl-,monosodium salt;5-Ethyl-5-phenylbarbituric acid sodium;Gardenal sodium;Luminal sodium;Phenemalum;Phenobal sodium;Phenobarbital sodium;Phenobarbitone sodium;Sodium 5-ethyl-5-phenylbarbiturate;Sodium luminal;Sodium phenobarbital;Sodium phenobarbitone;Sodium phenylethylbarbiturate;Soluble phenobarbital;Soluble phenobarbitone;Sol phenobarbital;Sol phenobarbitone;Sodium phenylethylmalonylurea;Phenobal;Sodium ethylphenylbarbiturate;Linasen;125-36-0;8050-96-2
Categories:
Active Pharmaceutical Ingredients > Nervous System Drugs

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Description

Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y7 (2.2.2, Method II).

Phenobarbital sodium Basic Attributes

Molecular Weight：

254.22

Exact Mass：

254.06700

EC Number：

200-322-3

Characteristics

PSA：

81.59000

XLogP3：

0.54170

Appearance：

Sodium phenobarbital is an odorless white crystalline powder. Aqueous solutions are alkaline to litmus and phenolphthalein (pH approximately 9.3). Bitter taste. A narcotic.

Melting Point：

175°C

Water Solubility：

H2O: >=10 g/100 mL at 20 ºC

Storage Conditions：

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Toxicity：

LD50 orally in rats: 660 mg/kg (Schaffarzick, Brown)

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

UN 2811 6.1/PG 3

wgk germany：

hazard class code：

25-40-43

safety instructions：

22-36/37/39-45

RTECS Number：

CQ7000000

Marks：

Precautionary statement(s)：

P280-P301 + P310

Hazard Statements：

H301-H317-H351

Phenobarbital sodium Use and Manufacturing

Used as a sedative and anticonvulsant