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(-)-Dihydroquinine

(-)-Dihydroquinine structure

(-)-Dihydroquinine 

structure
  • CAS No:

    522-66-7

  • Formula:

    C20H26N2O2

  • Chemical Name:

    (-)-Dihydroquinine

  • Synonyms:

    Cinchonan-9-ol,10,11-dihydro-6′-methoxy-,(8α,9R)-;Hydroquinine;(8α,9R)-10,11-Dihydro-6′-methoxycinchonan-9-ol;Dihydroquinine;10,11-Dihydroquinine;(-)-Dihydroquinine;(-)-10,11-Dihydroquinine;NSC 41799;(-)-Hydroquinine;7761-99-1;23495-97-8;28639-01-2;1089761-33-0;1217598-14-5;2244812-98-2;2244813-00-9

  • Categories:

    Inorganic Chemistry  >  Inorganic Salts

Description

Hydroquinone is a inhibitor of melanin synthesis, serves as a skin whitener and is usually available in cosmetics or on prescription[1].Hydroquinone can be used in the preparation of oxidized light-emitting materials such as lucigenin by inducing the production of hydrogen peroxide in the presence of basic compounds.Hydroquinone (HQ) is the most abundant quinine present in cigarette tar it can enter the circulation via the lungs and can interact with cellular targets throughout the body,


Hydroquinine is a cinchona alkaloid.

(-)-Dihydroquinine Basic Attributes

326.43

326.43

208-334-0

31J3Q51T6L

C - Cardiovascular system|M - Musculo-skeletal system

2933990090

Characteristics

45.6

3.1

1.2±0.1 g/cm3

172.5 °C

498.4°C at 760 mmHg

255.2±24.6 °C

1.626

99.99mg/L(20 ºC)

D18 -142° (alc); D20 -236° (c = 0.82 in 0.1N H2SO4)

Safety Information

III

6.1(b)

1544

3

36/37/38

26-36

Xi

P261-P305 + P351 + P338

H315-H319-H335

|Warning|H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, and P501|Aggregated GHS information provided by 40 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. (See all compounds classified as Anti-Arrhythmia Agents.)|Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS. (See all compounds classified as Parasympatholytics.)

dihydroquinidine

Computed Properties

Molecular Weight:326.4
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:326.199428076
Monoisotopic Mass:326.199428076
Topological Polar Surface Area:45.6
Heavy Atom Count:24
Complexity:432
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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