Adenosine
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Adenosine
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CAS No:
58-61-7
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Formula:
C10H13N5O4
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Chemical Name:
Adenosine
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Synonyms:
Adenosine;Adenine riboside;9-β-D-Ribofuranosyladenine;β-D-Adenosine;9H-Purin-6-amine,9-β-D-ribofuranosyl-;β-D-Ribofuranose,1-(6-amino-9H-purin-9-yl)-1-deoxy-;β-D-Ribofuranoside,adenine-9;β-Adenosine;Boniton;Myocol;Nucleocardyl;Sandesin;Riboadenosine;9-β-D-Ribofuranosyl-9H-purin-6-amine;D-Adenosine;Adenocard;Adenoscan;Adrekar;Adenocor;NSC 7652;24: PN: WO2007053194 SEQID: 49 claimed sequence;26: PN: WO2007053194 SEQID: 49 claimed sequence;27: PN: WO2007053194 SEQID: 49 claimed sequence;Adenogesic;NQZ-012;46946-45-6;46969-16-8
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CAS No:
Description
Adenosine is an important nucleoside composed of adenine and ribose. It is a white crystalline odorless powder with slightly salty or bitter taste. It is easily soluble in hot water and almost insoluble in alcohol. It is separated by yeast nucleic acid hydrolysis. Adenosine is a nucleoside consisting of an adenine molecule connected to a ribose molecule (ribofuran) part by a β-N9-glucoside bond. Adenosine is involved in energy transfer in the form of adenosine triphosphate (ATP) and adenosine diphosphate (ADP) and in signal transduction in the form of cyclic adenosine phosphate (cAMP). It is a purine D-ribonucleoside, a member of the adenosine family, which is functionally related to adenine and has neuroregulatory, cytoprotective, anti-inflammatory, and cardioprotective effects.
Characteristics
140
-1.1
White Crystalline Powder
2.1±0.1 g/cm3
235.5 °C
676.3°C at 760 mmHg
362.8±34.3 °C
1.907
soluble in water, ammonium hydroxide and dimethyl sulfoxide. Insoluble in ethanol.
2-8°C
6.0X10-15 mm Hg at 25 deg C (est)
Peritoneal-mouse LD50: 500 mg/kg
Flammable; burning releases toxic nitrogen oxide fumes
D11 -61.7° (c = 0.706 in water); 9D -58.2° (c = 0.658 in water)
Odorless
Mild, saline, or bitter taste
pH = 4.5-7.5 (solution of 3 mg/mL adenosine and 9 mg/mL sodium chloride in water)
Safety Information
NONH for all modes of transport
2
36/37/38
24/25-36/37/39-26
AU7175000
Treasury is ventilated, low temperature and dry; stored separately from food materials
Stable. Incompatible with strong oxidizing agents.
P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362
H315
Adenosine Use and Manufacturing
Antiviral drugs.Antiarrhythmic drugs can turn paroxysmal supraventricular tachycardia into sinus rhythm. Used for supraventricular arrhythmias related to atrioventricular.In the pharmaceutical industry, it is mainly used to manufacture adenosine arabinoside; adenosine triphosphate; the main raw material for drugs such as coenzyme and its series products cyclic adenosine monophosphate
Price Analysis
Drug Function and Efficacy
For diagnostic purposes
Registered Holders
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EUTICALS SPA
Active
United States
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Pharma Waldhof GmbH
Active
Germany
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Yuanda Life Sciences (Liaoning) Co., Ltd.
Active
China
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