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Yatein

Yatein structure

Yatein 

structure
  • CAS No:

    40456-50-6

  • Formula:

    C22H24O7

  • Chemical Name:

    Yatein

  • Synonyms:

    2(3H)-Furanone,4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(3,4,5-trimethoxyphenyl)methyl]-,(3R,4R)-;2(3H)-Furanone,4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(3,4,5-trimethoxyphenyl)methyl]-,(3R-trans)-;(3R,4R)-4-(1,3-Benzodioxol-5-ylmethyl)dihydro-3-[(3,4,5-trimethoxyphenyl)methyl]-2(3H)-furanone;(-)-trans-3-(3,4-Methylenedioxybenzyl)-2-(3,4,5-trimethoxybenzyl)butyrolactone;Yatein;Dihydroanhydropodorhizol;(-)-Yatein;Deoxypodorhizon;(-)-Deoxypodorhizone;Deoxypodorhizone;153061-92-8

  • Categories:

    Natural Products  >  Lignans

Description

Yatein is a lignan isolated from A. chilensis, with antiproliferative activity[1]. Yatein suppresses herpes simplex virus type 1 (HSV-1 ) replication by interruption the immediate-early gene expression[2].


Dihydroanhydropodorhizol is a member of the class of butan-4-olides carrying 3,4,5-trimethoxybenzyl and (1,3-benzodioxol-5-yl)methyl substituents at positions 3 and 4 respectively. It has a role as a plant metabolite. It is a lignan, a butan-4-olide, a member of methoxybenzenes and a member of benzodioxoles.

Yatein Basic Attributes

400.42176

400.42

DTXSID50193471

Characteristics

72.45000

3.06

1.3±0.1 g/cm3

564.9±45.0 °C at 760 mmHg

246.2±28.8 °C

1.577

Drug Information

yatein

Computed Properties

Molecular Weight:400.4
XLogP3:3.8
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:400.15220310
Monoisotopic Mass:400.15220310
Topological Polar Surface Area:72.4
Heavy Atom Count:29
Complexity:541
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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