Phenol, 2-amino-4-arsinyl-, hydrochloride (1:1)
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Phenol, 2-amino-4-arsinyl-, hydrochloride (1:1)
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CAS No:
538-03-4
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Formula:
C6H6AsNO2.ClH
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Chemical Name:
Phenol, 2-amino-4-arsinyl-, hydrochloride (1:1)
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Synonyms:
Phenol,2-amino-4-arsinyl-,hydrochloride (1:1);Phenol,2-amino-4-arsenoso-,hydrochloride;Phenol,2-amino-4-arsenoso-,monohydrochloride;2-Amino-4-arsenosophenol hydrochloride;3-Amino-4-hydroxyphenylarsine oxide hydrochloride;Arseno 39;Arsenosan;Arsenoxide;Ehrlich 5;Fontarsan;Mapharsal;Mapharsen;Mapharside;Oxiarsolan;Oxophenarsine hydrochloride;Arsphenoxide;Metarsen;Treparsen;Maspharside;NSC 627725
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CAS No:
Phenol, 2-amino-4-arsinyl-, hydrochloride (1:1) Basic Attributes
236.50800
235.94600
208-682-3
OG8JNR786U
3087|627725
DTXSID50202077
Phenol, 2-amino-4-arsinyl-, hydrochloride (1:1) Use and Manufacturing
In 1930, the oxidised compound Oxophenarsine,
containing an As＝O unit, was identified as the active ingredient and was later marketed under the trade
name Mapharsen. Mapharsen was used until the 1940s when it was replaced by Penicillin. Mapharsen was
actually synthesised in Ehrlich’s laboratory as compound number 5, but it was believed to be too toxic for
any clinical application .
Generally, the use of arsenic-based drugs has ceased, especially as a result of the development of Penicillin.
Nevertheless, Melarsoprol and an arsenic-based drug closely related to Atoxyl are licensed to treat sleeping
sickness.
Computed Properties
Molecular Weight:235.50
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Exact Mass:234.938126
Monoisotopic Mass:234.938126
Topological Polar Surface Area:63.3
Heavy Atom Count:11
Complexity:131
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
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