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Ditilin

Ditilin structure

CAS No:
541-19-5
Formula:
C14H30N2O4.2I
Chemical Name:
Ditilin
Synonyms:
Ethanaminium,2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-,iodide (1:2);Choline,iodide,succinate (2:1);Ethanaminium,2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-,diiodide;Choline,iodide succinate;Ascuron;Bis(β-dimethylaminoethyl)succinate dimethiodide;Celocurin;Curacit;Succinylcholine iodide;Succinyldicholine iodide;O,O-Succinyldicholine iodide;Suxamethonium iodide;Ditilin iodide;Celocurine;Succinyldicholine diiodide;Succinylcholine diiodide;Ditylin;Ditilin;Ditilin diiodide
Categories:
Organic Chemistry > Amides

Description

A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.

Ditilin Basic Attributes

Molecular Weight：

544.20800

Exact Mass：

544.03000

EC Number：

208-770-1

UNII：

PG6H2852BK

HScode：

2923900090

Characteristics

PSA：

52.60000

Density：

1.76 g/cm³

Melting Point：

244 °C

Toxicity：

LD50 ipr-mus: 5 mg/kg AEPPAE 228,371,56

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

UN 3249

Drug Information

MeSH：

Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. (See all compounds classified as Neuromuscular Depolarizing Agents.)

MeSH Entry Terms：

Anectine

Computed Properties

Molecular Weight:544.21
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:544.02950
Monoisotopic Mass:544.02950
Topological Polar Surface Area:52.6
Heavy Atom Count:22
Complexity:284
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes