(+)-Euphol
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(+)-Euphol
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CAS No:
514-47-6
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Formula:
C30H50O
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Chemical Name:
(+)-Euphol
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Synonyms:
Lanosta-8,24-dien-3-ol,(3β,13α,14β,17α)-;13α,14β,17βH-Lanosta-8,24-dien-3β-ol;Euphol;(3β,13α,14β,17α)-Lanosta-8,24-dien-3-ol;Euphadienol;Eupha-8,24-dienol;5α-Eupha-8,24-dien-3β-ol;(+)-Euphol;Eupha-8,24-dien-3β-ol;(+)-Eupha-8,24-dien-3β-ol;NSC 36571;α-Euphol;13879-03-3
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CAS No:
Description
Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain[1].
(+)-Euphol Use and Manufacturing
antineoplastic, antiproliferative, antiinflammatory, antinociceptive
Computed Properties
Molecular Weight:426.7
XLogP3:8.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:426.386166214
Monoisotopic Mass:426.386166214
Topological Polar Surface Area:20.2
Heavy Atom Count:31
Complexity:767
Undefined Atom Stereocenter Count:7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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