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7-Hydroxyquinoline

7-Hydroxyquinoline structure

7-Hydroxyquinoline 

structure

Description

white to light yellow crystal powder


Quinolin-7-ol is a monohydroxyquinoline carrying a hydroxy substituent at position 7.

7-Hydroxyquinoline Basic Attributes

145.16

145.16

209-457-2

D2G6YUK7ZJ

87630

DTXSID7060380

2933499090

Characteristics

29.1

1

Beige to pale brown Powder

1.3±0.1 g/cm3

239 °C

312.9°C at 760 mmHg

143.1±20.4 °C

1.691

454.3mg/L(20 ºC)

Safety Information

IRRITANT

36/37/38-20/21/22-22

36/37/39-26

VC4160000

Xn,Xi

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

H302

|Warning|H302 (40%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 5 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

7-hydroxyquinoline

7-Hydroxyquinoline Use and Manufacturing

Methods of Manufacturing

General procedure: General procedure for synthesis of quinolines from anilines and ADA was carried out in Panasonic NN-K5541JF microwave oven reactor equipping a magnetic stirring device. The typical procedures were as follows: ADA (1mmol), excessive anilines (4mmol) and solid catalyst were charged into a round-bottom ask; and then, the mixtures was placed into microwave reactor. The reaction was conducted by continuous microwave irradiation for 1–40 min under refluxing and stirring condition. Finally, the resulting products were determined by GC–MS of Varian Saturn 2200/ CP-3800 gas chromatography–mass spectrometry equipped with two CP8944 capillary columns (VF-5, 30m×0.25mm×0.25 μm).

7-Quinolinol: INACTIVE

Computed Properties

Molecular Weight:145.16
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Exact Mass:145.052763847
Monoisotopic Mass:145.052763847
Topological Polar Surface Area:33.1
Heavy Atom Count:11
Complexity:138
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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