dodecyl hydrogen sulphate

266.4

266.40

205-791-8

DIQ16UC154

TSCA listed

DTXSID0042088

1.1558 (rough estimate)

25-27 °C

379.6°C (rough estimate)

1.5220 (estimate)

-3.29±0.18(Predicted)

5.5×101mol/(m3Pa) at 25℃, HSDB (2015)

PROTEIN BINDING ENERGY: -11 KCAL/MOLE

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

SURFACTANTS WERE INCORPORATED INTO MIXT WITH AMMONIUM THIOGLYCOLATE & APPLIED TO CLIPPED SKIN OF RABBITS DAILY FOR 20 DAYS. DAILY DOSAGE CAUSING 50% MORTALITY WAS DETERMINED. HIGHEST ACTIVITY WAS FOUND WITH TECHNICAL LAURYL SULFATE.

LD50 Rat oral 1300 mg/kg

Dodecyl sulfate's production and use as a surfactant(1) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1.0X10+4(SRC), determined from a structure estimation method(2), indicates that dodecyl sulfate is expected to be immobile in soil(SRC). Volatilization of dodecyl sulfate from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 1.8X10-7 atm-cu m/mole(SRC), using a fragment constant estimation method(3). Dodecyl sulfate is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 3.2X10-8 mm Hg(SRC), determined from a fragment constant method(4). Biodegradation of dodecyl sulfate in soil may be an important fate process since it is fairly biodegradable in aqueous biodegradation tests(5).|AQUATIC FATE: Based on a classification scheme(1) and an estimated Koc value of 1.0X10+4(SRC), determined from an estimation method(2), dodecyl sulfate is expected to adsorb to suspended solids and sediment in water(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 1.8X10-7 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 71(SRC), from an estimated log Kow of 2.4(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is moderate. Biodegradation of dodecyl sulfate in water may be an important fate process since it is fairly biodegradable in aqueous biodegradation tests(8).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dodecyl sulfate, which has an estimated vapor pressure of 3.2X10-8 mm Hg at 25 °C(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase dodecyl sulfate may be removed from the air by wet and dry deposition(SRC).

An estimated BCF of 71 was calculated for dodecyl sulfate(SRC), using an estimated log Kow of 2.4(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate.

Using a structure estimation method based on molecular connectivity indices(1), the Koc for dodecyl sulfate can be estimated to be 1.0X10+4(SRC). According to a classification scheme(2), this estimated Koc value suggests that dodecyl sulfate is expected to be immobile in soil.

The Henry's Law constant for dodecyl sulfate is estimated as 1.8X10-7 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that dodecyl sulfate is expected to be essentially nonvolatile from water surfaces(2). Dodecyl sulfate is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 3.2X10-8 mm Hg(SRC), determined from a fragment constant method(3).

Occupational exposure to dodecyl sulfate may occur through inhalation and dermal contact with this compound at workplaces where dodecyl sulfate is produced or used. The general population may be exposed through dermal contact of consumer products containing this compound. (SRC)

Agents that modify interfacial tension of water; usually substances that have one lipophilic and one hydrophilic group in the molecule; includes soaps, detergents, emulsifiers, dispersing and wetting agents, and several groups of antiseptics. (See all compounds classified as Surface-Active Agents.)

EIGHTY-EIGHT PERCENT OF RADIOLABEL FROM (14)C-LABELED PROPIONYL ERYTHROMYCIN LAURYL SULFATE EXCRETED IN URINE IN 24 HR FOLLOWING SINGLE ORAL DOSE. MORE THAN 95% WAS BUTYRIC ACID 4-SULFATE, A DERIVATIVE OF LAURYL SULFATE MOIETY.

METAB OF LAURYL SULFATE IN MAN & RAT WAS VIRTUALLY COMPLETE &...INDEPENDENT OF NATURE OF SALT FORM. COMPD WAS METABOLIZED BY OMEGA-HYDROXYLATION & WAS EVENTUALLY CONVERTED INTO BUTYRIC ACID 4-SULFATE. ... IN MAN A SECOND ROUTE...INVOLVED CLEAVAGE OF SULFATE LINKAGE & OXIDN OF RESULTING ALC /9-16% OF DOSE/.|BUTYRIC ACID 4-SULFATE PROBABLY ARISES BY OMEGA-OXIDATION OF DODECYL SULFATE TO A FATTY ACID-LIKE COMPD, WHICH IS THEN DEGRADED BY BETA-OXIDATION.|BUTYRIC ACID 4-SULFATE, PRODUCT OF DODECYL SULFATE METAB, WAS PARTIALLY DEGRADED NONENZYMICALLY IN RATS TO INORG SULFATE IONS & GAMMA-BUTYROLACTONE. THE LATTER COMPD MAY BE CONVERTED TO GAMMA-HYDROXYBUTYRATE BY ENZYME LACTONASE.

SHAMPOOS CONTAINING DODECYL SULFATE DID NOT IRRITATE SKIN OF HEALTHY ADULTS OR OF ELDERLY PERSONS WITH VARIETY OF COMMON DISORDERS.|SKIN IS SENSITIZED BY SYNTHETIC DETERGENTS CONTAINING, IN MOST CASES 22% OF ACTIVE COMPONENT AS LAURYL SULFATE, SULFONOL, CATION-ACTIVE AND NON-IONOGENIC PREPN.|Moderately toxic by ingestion.

ammonium dodecyl sulfate

ESSENTIALLY 100% AS A CHEM INT FOR SALTS USED AS SURFACTANTS (1976)

Sulfuric acid, monododecyl ester: ACTIVE