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Thonzonium bromide

Thonzonium bromide structure

CAS No:
553-08-2
Formula:
C32H55N4O.Br
Chemical Name:
Thonzonium bromide
Synonyms:
1-Hexadecanaminium,N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]-N,N-dimethyl-,bromide (1:1);Ammonium,hexadecyl[2-[(p-methoxybenzyl)-2-pyrimidinylamino]ethyl]dimethyl-,bromide;Hexadecyl[2-[(p-methoxybenzyl)-2-pyrimidinylamino]ethyl]dimethylammonium bromide;1-Hexadecanaminium,N-[2-[[(4-methoxyphenyl)methyl]-2-pyrimidinylamino]ethyl]-N,N-dimethyl-,bromide;NC 1264;Cetyl[2-[(p-methoxybenzyl)-2-pyrimidinylamino]ethyl]dimethylammonium bromide;N-(2-Pyrimidyl)-N-(p-methoxybenzyl)-N′,N′-dimethyl-N′-cetyl-N′-bromoethylenediamine;Thonzide;Thonzonium bromide;Tonzonium bromide
Categories:
Organic Chemistry > Amides

Description

Thonzonium bromide is a monocationic detergent. Target: AntibacterialA solution of Thonzonium bromide is a surfactant and a detergent that promotes tissue contact by dispersion and penetration of the cellular debris and exudate of the containing solution. Thonzonium bromide is used in cortisporin-TC ear drops to help penetration of active ingredients through cellular debris for its antibacterial action.

Thonzonium Bromide is a cationic surface-active compound. As an additive to pharmacologic formulations, thonzonium bromide causes dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication.

Thonzonium bromide Basic Attributes

Molecular Weight：

591.70900

Exact Mass：

590.35600

EC Number：

209-032-1

UNII：

JI2B19CR0R

NSC Number：

760359|5648

DSSTox ID：

DTXSID1045326

NCI Thesaurus Code：

C47754

HScode：

2933599550

Characteristics

PSA：

38.25000

XLogP3：

5.05350

Melting Point：

91.5 °C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

20/21/22-36/37/38-41

safety instructions：

26-36

Marks：

Precautionary statement(s)：

P261-P280-P301 + P312 + P330-P305 + P351 + P338 + P310

Hazard Statements：

H302 + H312 + H332-H315-H318-H335

GHS Classification：

|Danger|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P332+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

thonzonium bromide

Thonzonium bromide Use and Manufacturing

Uses

neuromuscular blocker Detergent.

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:591.7
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:22
Exact Mass:590.35592
Monoisotopic Mass:590.35592
Topological Polar Surface Area:38.2
Heavy Atom Count:38
Complexity:515
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes