8-Amino-1-naphthalenecarboxylic acid

There are many synthetic routes for preparing 1-amino-8-naphthoic acid from naphthalene or acenaphthene: (1) Naphthalene sulfonic acid is used to prepare peripheral acid from naphthalene, and then 1-amino-8- is prepared from peripheral acid. Naphthalene sulfonic acid is obtained by hydrolysis. (2) The phosgenation method is obtained by preparing 1-naphthylamine from naphthalene and 1-naphthalene isocyanate from 1-naphthylamine, and then hydrolyzing. (3) Naphthalene anhydride is prepared from acenaphthene through air-catalyzed oxygen, then oxidized, rearranged 1, 8-naphalactam, and finally obtained by hydrolysis. The method has simple process, saving raw materials and low cost.

Dye intermediate. Used in the production of anthracene anthrone, synthesis of brilliant orange RK, reduced gray BG, etc.

Molecular Weight:187.19
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:187.063328530
Monoisotopic Mass:187.063328530
Topological Polar Surface Area:63.3
Heavy Atom Count:14
Complexity:229
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes