Viridicatin
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Viridicatin
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CAS No:
129-24-8
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Formula:
C15H11NO2
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Chemical Name:
Viridicatin
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Synonyms:
2(1H)-Quinolinone,3-hydroxy-4-phenyl-;Carbostyril,3-hydroxy-4-phenyl-;3-Hydroxy-4-phenyl-2(1H)-quinolinone;Viridicatin;Viridicatine;2,3-Dihydroxy-4-phenylquinoline;2,6-Dihydroxy-4-phenylquinoline;3-Hydroxy-4-phenylquinolin-2-one;3-Hydroxy-4-phenylcarbostyril;3-Hydroxy-4-phenyl-2-quinolone;NSC 656625;126885-11-8;40357-49-1
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CAS No:
Description
Viridicatin is a hydroxyquinolone that is 3-hydroxyuinolin-2(1H)-one which is substituted at position 4 by a phenyl groups. Isolated from the mycelium of several Penicillium species, it exhibits strong antibiotic activity against M. tuberculosis and also against B. subtilis, S. aureus and S. cerevisiae. It has a role as an antibacterial agent and a Penicillium metabolite.
Characteristics
49.3
3.31300
1.323g/cm3
268 °C
476.7ºC at 760mmHg
242.1ºC
1.677
6.79E-10mmHg at 25°C
Viridicatin Use and Manufacturing
Viridicatin is a fungal metabolite produced by several species of Penicillium and formed by the rearrangement of the benzodiazepine, cyclopenin. Viridicatin exhibits potent selective activity against Mycobacterium tuberculosis, but is inactive against most other bacteria.
Computed Properties
Molecular Weight:237.25
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:237.078978594
Monoisotopic Mass:237.078978594
Topological Polar Surface Area:49.3
Heavy Atom Count:18
Complexity:369
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes