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Cyanoacetic acid hydrazide

Cyanoacetic acid hydrazide structure

CAS No:
140-87-4
Formula:
C3H5N3O
Chemical Name:
Cyanoacetic acid hydrazide
Synonyms:
Acetic acid,2-cyano-,hydrazide;Acetic acid,cyano-,hydrazide;AB-42;Armazal;Cyacetacide;Cyacetazide;Cyanacethydrazide;Cyanacetic acid hydrazide;Cyanacetohydrazide;Cyanacetylhydrazide;Cyanazide;Cyanizide;Cyanoacetic acid hydrazide;Cyanoacetohydrazide;Cyazide;Dictycide;Dictyzide;Helmox;Hidacian;Leandin;Malonitrile hydrazide;Malononitrile hydrazide;Neohydrazid;Reacid;Reazide;Cyanoacethydrazide;α-Cyanoacetohydrazide;Cyanoacetyl hydrazide;(Cyanoacetyl)hydrazine;Mackreazid;Tsiazid;Cyazid;Cyacetazid;Reazid;Cianazil;Cyacetacid;Hidaciann;2-Cyanoacetohydrazide;Cyanoacetic hydrazide;(α-Cyanoacetyl)hydrazine;Cyanoethanoic hydrazide;2-Cyanoacethydrazide;2-Cyanoacetylhydrazide;NSC 24261;2-Cyano acetyl hydrazine;2-Cyanoacetic acid hydrazide
Categories:
Chemical Reagents > Organic Reagents

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Description

BROWN GRANULAR CRYSTALLINE POWDER

Cyanoacetic acid hydrazide Basic Attributes

Molecular Weight：

99.09

Exact Mass：

99.09

BRN：

1751498

EC Number：

205-437-2

UNII：

40H59YCS67

NSC Number：

24261

DSSTox ID：

DTXSID9046572

Color/Form：

STOUT PRISMS FROM ALCOHOL

HScode：

29280090

Characteristics

PSA：

78.9

XLogP3：

-1.3

Density：

1.3131 (rough estimate)

Melting Point：

114.5-115 °C

Boiling Point：

185.55°C (rough estimate)

Flash Point：

199.1±24.0 °C

Refractive Index：

1.4500 (estimate)

Water Solubility：

H2O: almost transparency;SOL IN ALCOHOL; VERY SOL IN WATER; PRACTICALLY INSOL IN ETHER

PH：

VERY SLIGHTLY ACID TO LITMUS; AQ SOLN BECOME DISCOLORED AFTER FEW DAYS & PH BECOMES ALKALINE

Safety Information

Packing level：

III

Hazard category：

6.1

Transport codes：

UN 2811 6.1/PG 3

wgk germany：

hazard class code：

20/21/22-36/37/38

safety instructions：

26-28-36/37/39-45

RTECS Number：

AG4200000

Marks：

Xn,Xi

Hazard note：

Irritant

Stability/Shelf Life：

RAPIDLY DECOMP BY HEAT

Precautionary statement(s)：

P261-P280-P301 + P310-P305 + P351 + P338

Hazard Statements：

H301-H312-H315-H319-H332-H335

GHS Classification：

|Danger|H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 44 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Therapeutic Uses：

MEDICATION (VET): ORALLY & SC, FOR ELIMINATION OR REDUCTION OF LUNGWORM POPULATIONS FROM CATTLE, DONKEYS, GOATS, SHEEP, SWINE, SOME FUR BEARING ANIMALS & POSSIBLY SOME SWINE & BIRDS. COMBINED WITH PHENOTHIAZINE THERAPY...IT HAS THE ADVANTAGE THAT THE LATTER KILLS THE FIRST STAGE DICTYOCAULUS LARVAE IN INTESTINAL TRACT.|MEDICATION (VET): DOSAGE: CATTLE, GOATS, SHEEP, SWINE, DONKEYS 15-17 MG/KG SC, ORAL; PHEASANTS 0.05% LEVEL IN DRINKING WATER.

Mechanism of Action：

VET: PARASITES LOOSEN THEIR HOLD AFTER TREATMENT & ARE MOVED UPWARD BY CILIARY ACTION. GOOD RESULTS ARE MECHANICALLY IMPAIRED BY TENACIOUS MUCOUS OR INFLAMMATORY EXUDATES.

Antidote：

VET: THE PHYSIOLOGICAL ANTIDOTE IN POISONING...IS PYRIDOXINE (VITAMIN B6) BUT PALLIATIVE MEASURES MAY BE TAKEN BY ADMIN OF SEDATIVES.

MeSH Entry Terms：

alpha-cyanoacetic acid hydrazide

Cyanoacetic acid hydrazide Use and Manufacturing

Methods of Manufacturing

PREPD BY BOILING ETHYL OR METHYL CYANOACETATE WITH HYDRAZINE HYDRATE IN ALCOHOL: ROTHENBURG, BER 27, 687 (1894); DARAPSKY, HILLERS, J PRAKT CHEM 92[2], 313 (1915); KLOSA, ARCH PHARM 288, 453 (1955).

Uses

MEDICATION (VET)|MEDICATION|ANTITUBERCULAR

Formulations：

PREPN OF DOSAGE FORMS: MUSET, US PATENT 2,849,369 (1958 TO LABS 0M).

Computed Properties

Molecular Weight:99.09
XLogP3:-1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:99.043261792
Monoisotopic Mass:99.043261792
Topological Polar Surface Area:78.9
Heavy Atom Count:7
Complexity:111
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 140-87-4

Grade: Industrial Grade

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CAS No.: 140-87-4

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Guide of Cyanoacetic acid hydrazide

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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Cyanoacetic acid hydrazide

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