2-(Quinolin-2-yl)ethanol

2-fquinolin-2-yl)ethanol: Ethyl 2-quinolylacetate (8.6 g, 42.8 mmol) in diethyl ether (400 mL) was cooled to -78al .2) 2-Quinolin-2-yl-ethanol To a cold (0 °C) solution of the compound from Example al . l (10 g, 45 mmol) in THF (200 ml) was added L1AIHa1.2a) 2-Quinolin-2-yl-ethanol To a cold (0 C.) solution of the compound from Example a1.1a (10 g, 45 mmol) in THF (200 mL) was added LiAlH4 (2.65 mg, 70 mmol) in small portions over a period of 5 min. The resulting mixture was stirred for 1 h. Water was added dropwise very slowly. Then more water and EA were added. The organic phase was collected, dried and concentrated. The residue was purified by silica gel chromatography (PE/EA=2:1) to give the title compound as a yellow solid (2.5 g, 30%). LCMS (ESI+): m/z 174 (M+H)+, Rt: 0.75 min.

Molecular Weight:173.21
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:173.084063974
Monoisotopic Mass:173.084063974
Topological Polar Surface Area:33.1
Heavy Atom Count:13
Complexity:160
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes